ArticleJournal of human genetics2007
Comparison of ENCODE region SNPs between Cebu Filipino and Asian HapMap samples.
Article in Journal of human genetics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- DISSCO: direct imputation of summary statistics allowing covariates.Bioinformatics (Oxford, England) · 2015Article
- A comprehensive SNP and indel imputability database.Bioinformatics (Oxford, England) · 2013Article
- Article
- Identifying highly conserved and highly differentiated gene ontology categories in human populations.PloS one · 2011Article
- Comparison of genome-wide variation between Malawians and African ancestry HapMap populations.Journal of human genetics · 2010Article
- Genome-wide association study of homocysteine levels in Filipinos provides evidence for CPS1 in women and a stronger MTHFR effect in young adults.Human molecular genetics · 2010Article
- TagSNP transferability and relative loss of variability prediction from HapMap to an admixed population.Journal of biomedical science · 2009Article
- Perspectives for Metabolomics in Human Nutrition: An Overview.Nutrition bulletin · 2008Article
- Association of FTO with obesity-related traits in the Cebu Longitudinal Health and Nutrition Survey (CLHNS) Cohort.Diabetes · 2008Article
- Using population mixtures to optimize the utility of genomic databases: linkage disequilibrium and association study design in India.Annals of human genetics · 2008Article
- Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
Patterns of linkage disequilibrium (LD) act as the framework for designing efficient association studies; these patterns are being studied and catalogued by The International HapMap Project. The current study assessed the transferability of tag SNPs chosen from HapMap panels to a cohort of 80 individuals from metro Cebu, Philippines, who participated in the Cebu Longitudinal Health and Nutrition Survey (CLHNS). The analyses focused on 627 single nucleotide polymorphisms (SNPs) in the central 40 kb within each of the 10 HapMap ENCODE regions. The similarity between the genetic variants in Cebu Filipino samples and HapMap panels was examined using allele frequency estimates, measures of pairwise linkage disequilibrium (LD), and haplotype frequency estimates. For these measures, strong correlations were observed between the Cebu Filipino samples and the Asian panels from HapMap, with the strongest correlations observed with the Han Chinese from Beijing (CHB) panel. Tag SNPs selected using the HapMap CHB panel were particularly effective at representing the genetic variation in Cebu Filipino samples. These results suggest that the HapMap data will be an effective resource for future studies in Cebu Filipino samples.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.