Evidence map›Paper›PMID 17635615›Full record

ArticleInsect molecular biology2007

Molecular characterization of the Aedes aegypti odorant receptor gene family.

J Bohbot, R J Pitts, H-W Kwon, M Rützler, H M Robertson, L J Zwiebel

Open access · greenAbstract read
In one paragraph

Article in Insect molecular biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 247 citations in OpenAlex.

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  9. A single-nucleus transcriptomic atlas of the adultbioRxiv : the preprint server for biology · 2025
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69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

J BohbotDepartment of Biological Sciences, Programs in Developmental Biology and Genetics, Centers for Chemical Biology and Molecular Neuroscience, The Institute for Global Health, Vanderbilt University, Nashville, TN 37235, USA.
R J Pitts
H-W Kwon
M Rützler
H M Robertson
L J Zwiebel
Vanderbilt University · USUniversity of Illinois Urbana-Champaign · US

Funding

Examination of Odorant Receptors in Vector MosquitoesR01AI056402 · NIAID · VANDERBILT UNIVERSITY · PI ZWIEBEL, LAURENCE J · 2003 to 2013
$4.0M
MOLECULAR GENETICS OF OLFACTION IN ANOPHELINE MOSQUITOESR01DC004692 · NIDCD · VANDERBILT UNIVERSITY · PI ZWIEBEL, LAURENCE J · 2000 to 2004
$1.1M
Gustatory and olfactory receptors of Anopheles gambiaeR01AI056081 · NIAID · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI ROBERTSON, HUGH M. · 2003 to 2006
$1.0M
NIAID NIH HHS AI056402NIAID NIH HHS AI56081NIAID NIH HHS R01 AI056081NIAID NIH HHS R01 AI056402NIDCD NIH HHS DC04692NIDCD NIH HHS R01 DC004692
6 · The paper itself

Abstract

The olfactory-driven blood-feeding behaviour of female Aedes aegypti mosquitoes is the primary transmission mechanism by which the arboviruses causing dengue and yellow fevers affect over 40 million individuals worldwide. Bioinformatics analysis has been used to identify 131 putative odourant receptors from the A. aegypti genome that are likely to function in chemosensory perception in this mosquito. Comparison with the Anopheles gambiae olfactory subgenome demonstrates significant divergence of the odourant receptors that reflects a high degree of evolutionary activity potentially resulting from their critical roles during the mosquito life cycle. Expression analyses in the larval and adult olfactory chemosensory organs reveal that the ratio of odourant receptors to antennal glomeruli is not necessarily one to one in mosquitoes.

Indexed as

AedesAnimalsAnophelesFemaleGene Expression ProfilingGene Expression Regulation, DevelopmentalGenome, InsectInsect VectorsLife Cycle StagesMaleMultigene FamilyReceptors, OdorantReceptors, Odorant

Identifiers

PMID17635615
PMCPMC3100214
OpenAlexW2047703671

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.