ArticleAging cell2007
Remodeling chromatin for senescence.
Article in Aging cell, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 36 citations in OpenAlex.
- Cellular Senescence and Aging in Myotonic Dystrophy.International journal of molecular sciences · 2022Review
- Identification and validation of pivotal genes related to age-related meniscus degeneration based on gene expression profiling analysis and in vivo and in vitro models detection.BMC medical genomics · 2021Article
- Human skin aging is associated with increased expression of the histone variant H2A.J in the epidermis.NPJ aging and mechanisms of disease · 2021Article
- Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype.Frontiers in cell and developmental biology · 2021Review
- Mechanisms underlying T cell ageing.Nature reviews. Immunology · 2019Review
- Defenses against Pro-oxidant Forces - Maintenance of Cellular and Genomic Integrity and Longevity.Radiation research · 2018Review
- Mechanisms and functions of cellular senescence.The Journal of clinical investigation · 2018Review
- The role of epigenetics in renal ageing.Nature reviews. Nephrology · 2017Review
- Homologous recombination-dependent repair of telomeric DSBs in proliferating human cells.Nature communications · 2016Article
- Are there roles for brain cell senescence in aging and neurodegenerative disorders?Biogerontology · 2014Review
- PIM-1 modulates cellular senescence and links IL-6 signaling to heterochromatin formation.Aging cell · 2014Article
- Epigenetics of aging and aging-related disease.The journals of gerontology. Series A, Biological sciences and medical sciences · 2014Review
- Cell senescence in myxoid/round cell liposarcoma.Sarcoma · 2014Article
- Crosstalk between chromatin state and DNA damage response in cellular senescence and cancer.Nature reviews. Cancer · 2012Article
- Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells.Nature cell biology · 2012Article
- Interplay between oncogene-induced DNA damage response and heterochromatin in senescence and cancer.Nature cell biology · 2011Article
- Senescent cells as a source of inflammatory factors for tumor progression.Cancer metastasis reviews · 2010Review
- Inflammatory networks during cellular senescence: causes and consequences.Trends in molecular medicine · 2010Review
- The senescence-associated secretory phenotype: the dark side of tumor suppression.Annual review of pathology · 2010Review
- Proteinopathy-induced neuronal senescence: a hypothesis for brain failure in Alzheimer's and other neurodegenerative diseases.Alzheimer's research & therapy · 2009Article
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cellular senescence is an irreversible proliferation arrest that contributes to tumor suppression and, perhaps, tissue aging. Senescence is frequently accompanied by an increase in nuclear heterochromatin, which is thought to promote proliferation arrest. In this issue, Medrano and co-workers describe new insights into the protein complexes that regulate these changes in chromatin structure.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.