Evidence map›Paper›PMID 17634462›Full record

ReviewThe New England journal of medicine2007

Vitamin D deficiency.

Michael F Holick

28 registry-linked trialsAbstract readReview
PubMed Publisher
In one paragraph

Review in The New England journal of medicine, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 28 registered trials, which are not on this map. Cited by 5,645 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5,645citing papers in PubMed, 9 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05613400 phase4unknown statusstarted 2022, after this paper: background citation

The Effect of Simvastatin on Bone Density in Postmenopausal Women With Type 2 Diabetes: a Double-blind, Randomized Active-comparator (Ezetimibe) Controlled Clinical Trial

Ran2022Enrolled240Registered outcomes7Posted comparisons0ConditionsDiabetes Mellitus, Type 2ArmsEzetimibe 10mg, Simvastatin 10mg
Open the trial in the graph
NCT01118806 completednot on this mapstarted 2010, after this paper: background citation

Vitamin D Deficiency in Medical Residence in Israel

TypeobservationalSponsorMeir Medical CenterRan2010 to 2011Enrolled106ConditionsVitamin D Deficiency
NCT01339741 naunknown statusnot on this mapstarted 2011, after this paper: background citation

The Efficacy of Vitamin D3 for the Treatment of Chronic Plaque Type Psoriatic Patients With Vitamin D Deficiency and Insufficiency: a Randomized Controlled Trial

TypeinterventionalSponsorChulalongkorn UniversityRan2011 to 2012Enrolled30ConditionsPsoriasis Vulgaris, Vitamin D DeficiencyArmsVitamin D3, Placebo
NCT01386736 phase4unknown statusnot on this mapstarted 2011, after this paper: background citation

Vitamin D Concentrations and Their Effect on Glucose Metabolism in Pediatrics

TypeinterventionalSponsorWeill Medical College of Cornell UniversityRan2011 to 2012Enrolled110ConditionsInsulin Resistance, Obesity, Vitamin D25 InsufficiencyArmsVitamin D drops, Placebo drops
NCT01397383 completednot on this mapstarted 2010, after this paper: background citation

The Effect of Serum Vitamin D Level and the Short Term Functional Outcomes After Total Hip Arthroplasty

TypeobservationalSponsorHospital for Special Surgery, New YorkRan2010 to 2014Enrolled219ConditionsVitamin D Deficiency
NCT01419743 terminatednot on this mapstarted 2011, after this paper: background citation

Randomized Controlled Trial: The Effects of Vitamin D Supplementation on In-vitro Fertilization Outcomes

TypeobservationalSponsorNorthwestern UniversityRan2011 to 2014Enrolled102ConditionsInfertility, Vitamin D Deficiency
NCT01499940 phase2terminatednot on this mapstarted 2012, after this paper: background citation

Phase II Study to Assess Prevention of Oxaliplatin-induced Neurotoxicity Through the Vitamin D Pathway

TypeinterventionalSponsorGerald Higa, PharmD.Ran2012 to 2012Enrolled9ConditionsNeurotoxicityArmsVitamin D3
NCT01781169 nacompletednot on this mapstarted 2011, after this paper: background citation

Health Effect of Oral Vitamin D Supplementation on Obese Chinese Males

TypeinterventionalSponsorShenzhen Center for Chronic Disease ControlRan2011 to 2012Enrolled43ConditionsObesity, Insulin ResistanceArmsOral supplementation of vitamin D
NCT01815437 nacompletednot on this mapstarted 2012, after this paper: background citation

Evaluation of Vitamin D in a Mushroom Supplement

TypeinterventionalSponsorBoston UniversityRan2012 to 2013Enrolled80ConditionsVitamin D DeficiencyArmsMushroom Vitamin D2, Cholecalciferol, Vitamin D2 - Ergocalciferol, Mushroom Extract
NCT01838447 phase2completednot on this mapstarted 2013, after this paper: background citation

Prevention of Post-Cardiac Surgery Vitamin D Deficiency in Children With Congenital Heart Disease: A Pilot Dose Evaluation Randomized Controlled Trial

TypeinterventionalSponsorChildren's Hospital of Eastern OntarioRan2013 to 2015Enrolled46ConditionsVitamin D Deficiency, Thoracic Surgery, Pediatric Disorders, Heart Defects, CongenitalArmsCholecalciferol
NCT01930539 nacompletednot on this mapstarted 2013, after this paper: background citation

Treatment of Vitamin D Deficiency in Intestinal Rehabilitation Clinic Patients With a Portable Ultraviolet B Lamp

TypeinterventionalSponsorUniversity of NebraskaRan2013 to 2015Enrolled11ConditionsVitamin D Deficiency, Short Bowel SyndromeArmsUltraviolet B lamp
NCT01991054 phase4completednot on this mapstarted 2013, after this paper: background citation

A Prospective, Double Blind, Randomized, Phase 4, Clinical Trial of The Effects of Vitamin D Supplementation on Patients With Type 2 Diabetes and Vitamin D Deficiency

TypeinterventionalSponsorHaEmek Medical Center, IsraelRan2013 to 2018Enrolled45ConditionsDiabetes Mellitus, Vitamin D DeficiencyArmsvitamin D3
NCT02186015 phase2completednot on this mapstarted 2015, after this paper: background citation

Safety, Feasibility and Efficacy of Vitamin D Supplementation in Women With Metastatic Breast Cancer (SAFE-D)

TypeinterventionalSponsorLoyola UniversityRan2015 to 2017Enrolled43ConditionsAdult Women, Metastatic Breast Cancer, Estrogen Receptor PositiveArmsCholecalciferol
NCT02301520 completednot on this mapstarted 2015, after this paper: background citation

Vitamin D Deficiency, Iodine Deficiency and Lead Levels in Haitian Infants and Children.

TypeobservationalSponsorBoston Children's HospitalRan2015 to 2015Enrolled299ConditionsVitamin D Deficiency, Iodine Deficiency, Hypothyroidism, Rickets
NCT02416193 phase2terminatednot on this mapstarted 2015, after this paper: background citation

Can Vitamin D3 Improve Cognitive Function in Individuals With Type 2 Diabetes? (THINK-D)

TypeinterventionalSponsorLoyola UniversityRan2015 to 2018Enrolled56ConditionsDiabetes, Executive DysfunctionArmsCholecalciferol
NCT02868827 phase2 / phase3terminatednot on this mapstarted 2017, after this paper: background citation

Cholecalciferol Supplementation in Critically Ill Patients With Severe Vitamin D Deficiency in Intensive Care Unit- A Randomized Controlled Trial.

TypeinterventionalSponsorKing Abdullah Medical CityRan2017 to 2019Enrolled127ConditionsVitamin D Deficiency, Critical IllnessArmsCholecalciferol, Milk (Nestle)
NCT03073720 completednot on this mapstarted 2017, after this paper: background citation

Correlation Between Follicular Fluid Levels of Bioavailable Vitamin D and Embryo Quality Markers: Euploid Status, Morphokinetics and Mitochondrial DNA Content Among UAE Women Undergoing an IVF Cycle

TypeobservationalSponsorART Fertility Clinics LLCRan2017 to 2019Enrolled43ConditionsVitamin D Deficiency
NCT03221972 completednot on this mapstarted 2010, after this paper: background citation

Vitamin D Nutritional Status and Its Related Factors for Chinese Children and Adolescents in 2010-2012

TypeobservationalSponsorLichen YangRan2010 to 2016Enrolled15,000ConditionsVitamin D Deficiency
NCT03232216 naunknown statusnot on this mapstarted 2017, after this paper: background citation

Vitamin D Supplementation in Patients With Operated Tibia Fracture and Low Vitamin D. Does it Improve Healing Rate?. Randomized Controlled Trial

TypeinterventionalSponsorHospital del Trabajador de SantiagoRan2017 to 2023Enrolled682ConditionsTibial Fractures, Vitamin D Deficiency, Fracture HealingArmsVitamin D3., Placebo
NCT03376490 completednot on this mapstarted 2012, after this paper: background citation

Cross-sectional Study of the Association of Muscle Strength, Tinetti Test (POMA) Scores and Other Predictor Variables With Serum Vitamin Levels (Vitamin B12, Vitamin D and Folate) in Elderly Patients With Type 2 Diabetes Mellitus

TypeobservationalSponsorSingHealth PolyclinicsRan2012 to 2014Enrolled56ConditionsMuscle Strength, Vitamin B 12 Deficiency, Folate Deficiency, Vitamin D Deficiency
NCT03584256 completednot on this mapstarted 2018, after this paper: background citation

Vitamin D Status Relate to Bone Mineral Density, Body Composition and Variey Cardiovascular Risk Factors Among Competitive Female Gymnasts and Swimmers After Winter Time

TypeobservationalSponsorUniversity of LjubljanaRan2018 to 2018Enrolled31ConditionsVitamin D Deficiency, Injuries, Cardiovascular Risk Factor, Nutritional Deficiency
NCT04091178 phase2completednot on this mapstarted 2013, after this paper: background citation

A PHASE II Multicentric Trial Evaluating a High Dose Vitamin D Supplementation to Correct the Vitamin D Deficiency for Breast Cancer Treated by Adjuvant Chemotherapy

TypeinterventionalSponsorInstitut du Cancer de Montpellier - Val d'AurelleRan2013 to 2017Enrolled57ConditionsBreast CancerArmsVITAMIN D
NCT04117750 nacompletednot on this mapstarted 2017, after this paper: background citation

Impact of Vitamin D Supplementation on the Cardiometabolic Status and Androgen Profile in Women With Polycystic Ovary Syndrome: Placebo-Controlled Clinical Trial

TypeinterventionalSponsorZagazig UniversityRan2017 to 2018Enrolled145ConditionsEvaluations, Diagnostic Self, Treatment AdherenceArmscholecalciferol (vit D3)
NCT04915963 phase3completednot on this mapstarted 2016, after this paper: background citation

Effect of a Single Mega-dose of Vitamin D3 Supplementation on Clinical Course in Non-deficient Patients Admitted in Intensive Care Unit

TypeinterventionalSponsorAssociation Tunisienne d'Etude & de Recherche sur l'AthéroscléroseRan2016 to 2019Enrolled340ConditionsDietary Supplements, Intensive Care Unit, Vitamin D Deficiency, Vitamin D ToxicityArmsVitamin D supplementation
NCT04986319 completednot on this mapstarted 2017, after this paper: background citation

The Level of Serum Vitamin D And Parathyroid Hormone Among Different Bangladeshi Population Groups

TypeobservationalSponsorBangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic DisordersRan2017 to 2021Enrolled556ConditionsVitamin D DeficiencyArmsSerum vitamin D assay
NCT05048511 withdrawnnot on this mapstarted 2016, after this paper: background citation

Evaluation of the Impact of Vitamine D Status on in Vitro Fertilization Outcomes in a Large Population of Infertile Women.

TypeobservationalSponsorNantes University HospitalRan2016 to 2016Enrolled0ConditionsInfertilityArmsvitamin D estimation
NCT06199102 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

The High Initial Dose of Monitored Vitamin D Supplementation in Preterm Infants. A Randomized Controlled Study.

TypeinterventionalSponsorPrincess Anna Mazowiecka Hospital, Warsaw, PolandRan2024 to 2027Enrolled130ConditionsVitamin D Deficiency, Osteopenia of Prematurity, Nephrolithiasis, Metabolic Bone DiseaseArmscholecalciferol/ Devikap
NCT06551688 completednot on this mapstarted 2024, after this paper: background citation

Influence of Preoperative Vitamin D Level on Postoperative Pain in Breast Cancer Surgery Patients: A Prospective Observational Study

TypeobservationalSponsorFayoum UniversityRan2024 to 2025Enrolled184ConditionsCancer Breast, Hypovitaminosis DArmsSerum 25(OH)D level
3 · Its place in the literature

Who cites it

5,645 citing papers in PubMed, 9 syntheses or guidelines pooled it.

  1. Effects of ultraviolet light exposure on blood pressure: a systematic review.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Pooled it
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  10. Trial
  11. Combined ProbioticMolecules (Basel, Switzerland) · 2026
    Trial
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  14. Kinetics and concentrations of circulating 25-hydroxyvitamin D using different vitamin D repletion regimens.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
    Trial
  15. Review
  16. Article
  17. Review
  18. Beyond total irradiance: a PCA-based filtering framework identifies wavelength-dependent biological signatures of sunlight exposure.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  19. Review
  20. Article

5,585 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Michael F HolickDepartment of Medicine, Section of Endocrinology, Nutrition, and Diabetes, the Vitamin D, Skin, and Bone Research Laboratory, Boston University Medical Center, Boston, MA 02118, USA. mfholick@bu.edu

Funding

YOGA INDUCED CHANGES IN BRAIN GABA LEVELSM01RR000533 · NCRR · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HOLICK, MICHAEL F. · 1985 to 2008
$19.4M
THE PHOTOBIOLOGY OF VITAMIN D3R01AR036963 · NIAMS · TUFTS UNIVERSITY BOSTON · PI HOLICK, MICHAEL F · 1986 to 2005
$1.8M
NCRR NIH HHS M01RR00533NIAMS NIH HHS AR36963
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAgedBone and BonesCalciumChildFemaleHumansKidney Failure, ChronicMaleOsteoporosisPhosphorusPrevalenceVitamin DVitamin D DeficiencyCalciumPhosphorusVitamin D

Identifiers

PMID17634462

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.