ArticleProteome science2007
Comparative proteomics reveal characteristics of life-history transitions in a social insect.
Article in Proteome science, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 69 citations in OpenAlex.
- ACmix-Swin Deep Learning of 4-Day-OldGenes · 2025Article
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- Paradoxes of Hymenoptera flight muscles, extreme machines.Biophysical reviews · 2022Review
- The Emerging Proteomic Research Facilitates in-Depth Understanding of the Biology of Honeybees.International journal of molecular sciences · 2019Review
- Antennal Protein Profile in Honeybees: Caste and Task Matter More Than Age.Frontiers in physiology · 2018Article
- Mitochondrial glycerol 3-phosphate facilitates bumblebee pre-flight thermogenesis.Scientific reports · 2017Article
- Article
- Sucrose Sensitivity of Honey Bees Is Differently Affected by Dietary Protein and a Neonicotinoid Pesticide.PloS one · 2016Article
- Detoxification mechanisms of honey bees (Apis mellifera) resulting in tolerance of dietary nicotine.Scientific reports · 2015Article
- Entometabolomics: applications of modern analytical techniques to insect studies.Entomologia experimentalis et applicata · 2015Review
- Article
- Aging and its modulation in a long-lived worker caste of the honey bee.The Journal of experimental biology · 2013Article
- Effects of Flight on Gene Expression and Aging in the Honey Bee Brain and Flight Muscle.Insects · 2012Article
- Worker honeybee brain proteome.Journal of proteome research · 2012Article
- IRS and TOR nutrient-signaling pathways act via juvenile hormone to influence honey bee caste fate.The Journal of experimental biology · 2011Article
- Flight restriction prevents associative learning deficits but not changes in brain protein-adduct formation during honeybee ageing.The Journal of experimental biology · 2011Article
- Article
- Differential proteomics in dequeened honeybee colonies reveals lower viral load in hemolymph of fertile worker bees.PloS one · 2011Article
- Differential gene expression and protein abundance evince ontogenetic bias toward castes in a primitively eusocial wasp.PloS one · 2010Article
- Lifetime- and caste-specific changes in flight metabolic rate and muscle biochemistry of honeybees, Apis mellifera.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2010Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
Abstract
backgroundHoney bee (Apis mellifera) workers are characterized by complex social behavior. Their life-history is dominated by a period of within-nest activity followed by a phase of long-distance flights and foraging. General insights into insect metabolism imply that foraging onset is associated with fundamental metabolic changes, and theory on social evolution suggests metabolic adaptations that are advantageous for the colony as a whole.
resultsHere we address the life-history characteristics of workers with LC-MS/MS based relative quantification of major proteins. Our approach includes: i. Calculation of a false positive rate for the identifications, ii. Support of relative protein quantification results obtained from spectral count by non-parametric statistics, and iii. Correction for Type 1 error inflation using a bootstrap iteration analysis. Our data are consistent with the use of glucose as the main fuel for honey bee flight. Moreover, the data delivers information on the expression of ATPsynthases/ATPases, and provide new insights into nurse- and forager-specific patterns of protection against oxidative stress.
conclusionThe results show the suitability of this approach to investigate fundamental biochemical changes in an insect, and provide new evidence for metabolic specializations that occur during the social ontogeny of worker honey bees.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.