ArticleSchizophrenia bulletin2007
A social deafferentation hypothesis for induction of active schizophrenia.
Article in Schizophrenia bulletin, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers, 2 of them syntheses that pooled it.
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Who cites it
86 citing papers in PubMed, 2 syntheses or guidelines pooled it, 193 citations in OpenAlex.
- The ethnic density effect in psychosis: a systematic review and multilevel meta-analysis.The British journal of psychiatry : the journal of mental science · 2021Pooled it
- Loneliness in Psychosis: A Meta-analytical Review.Schizophrenia bulletin · 2018Pooled it
- Identity and Psychosis Risk in Sexual Minority Youth: Temporal Dynamics of Identity and Suspiciousness Through Experience Sampling Methodology.Schizophrenia bulletin · 2026Article
- Loneliness patterns across time and subsequent risk of psychotic experiences, depression, anxiety, and diminished well-being in adolescents.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Loneliness despite social integration: subjective loneliness without social isolation as a risk factor for psychotic-like experiences.Annals of general psychiatry · 2026Article
- Social functioning, loneliness, and psychosis phenotype in the general population: a network analysis perspective.Social psychiatry and psychiatric epidemiology · 2026Article
- "A room of one's own": Exploring the role of delusions and social isolation on disorganisation in thought disorder.Social psychiatry and psychiatric epidemiology · 2026Article
- Advancing scientific understanding of the drive to socially engage: from broad constructs to transdiagnostic 'building blocks'.Molecular psychiatry · 2026Review
- Detecting Features of Interpersonal Difficulties in First-Person Accounts of Schizophrenia; Automated Linguistic and Network Analyses.Schizophrenia bulletin open · 2026Article
- Impact of early social isolation on social circuits and behavior: relevance to schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Review
- Loneliness in schizophrenia: Just loneliness.Annals of the New York Academy of Sciences · 2025Review
- Disparities in the incidence and prevalence of psychotic disorders among people with and without disabilities in south Korea: A national database study.Archives of public health = Archives belges de sante publique · 2025Article
- Visual hallucinations in Parkinson's disease are associated with deficits in social perception.Journal of Parkinson's disease · 2025Article
- Neurocognitive and social cognitive correlates of social exclusion in psychotic disorders: a 20-year follow-up cohort study.Social psychiatry and psychiatric epidemiology · 2025Article
- A case series of musical hallucinations in psychiatry of old age-in search of the sound of silence.Irish journal of medical science · 2024Review
- Exploring causal mechanisms of psychosis risk.Neuroscience and biobehavioral reviews · 2024Review
- Recent social stress and severity of auditory hallucinations.Schizophrenia research · 2024Article
- From Social Isolation to Social Justice: The Neuroscience of Solitary Confinement.Biological psychiatry · 2024Article
- Psychiatry and sensation: the epigenetic links.Epigenomics · 2024Review
- Felt presence and its determinants in young adults: results from three independent samples.Frontiers in psychiatry · 2024Article
26 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The "social brain" of humans reflects widespread neural resources dedicated to understanding the conversational language, emotionality, states of mind, and intentions of other persons. A social deafferentation (SDA) hypothesis for induction of active schizophrenia is proposed. Analogous to hallucinations produced by sensory deafferentation, such as phantom limb, the SDA hypothesis assumes that high levels of social withdrawal/isolation in vulnerable individuals prompt social cognition programs to produce spurious social meaning in the form of complex, emotionally compelling hallucinations and delusions representing other persons or agents. Arguments against the SDA hypothesis are discussed, and predictions deriving from the hypothesis are offered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.