SynthesisBMJ (Clinical research ed.)2007
Dressings for venous leg ulcers: systematic review and meta-analysis.
Synthesis in BMJ (Clinical research ed.), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 28 papers, 7 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
28 citing papers in PubMed, 7 syntheses or guidelines pooled it, 146 citations in OpenAlex.
- A meta-review of the impact of compression therapy on venous leg ulcer healing.International wound journal · 2023Pooled it
- Hydrogel dressings for venous leg ulcers.The Cochrane database of systematic reviews · 2022Pooled it
- Alginate dressings for venous leg ulcers.The Cochrane database of systematic reviews · 2015Pooled it
- Foam dressings for venous leg ulcers.The Cochrane database of systematic reviews · 2013Pooled it
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate healthcare interventions: explanation and elaboration.BMJ (Clinical research ed.) · 2009Guideline
- The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration.PLoS medicine · 2009Guideline
- The effectiveness of hydrocolloid dressings versus other dressings in the healing of pressure ulcers in adults and older adults: a systematic review and meta-analysis.Revista latino-americana de enfermagemPooled it
- Clinical evaluation of the efficacy and safety of a medical device in various forms containing Triticum vulgare for the treatment of venous leg ulcers - a randomized pilot study.Drug design, development and therapy · 2015Trial
- Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial.International wound journal · 2013Trial
- A randomised comparative trial on the use of a hydrogel with tepescohuite extract (Mimosa tenuiflora cortex extract-2G) in the treatment of venous leg ulcers.International wound journal · 2012Trial
- Effectiveness of acupuncture, special dressings and simple, low-adherence dressings for healing venous leg ulcers in primary healthcare: study protocol for a cluster-randomized open-labeled trial.BMC complementary and alternative medicine · 2008Trial
- Pilot study of homologous platelet gel in venous ulcers.Anais brasileiros de dermatologiaTrial
- Synergistic effect of octenidine gel and hydrogel dressing in the treatment of venous leg ulcers.Frontiers in pharmacology · 2026Article
- [Low-dose topical recombinant human granulocyte-macrophage colony-stimulating factor (rhu GM-CSF) therapy for chronic venous leg ulcers, 10-year follow-up].Dermatologie (Heidelberg, Germany) · 2023Article
- Managing the delivery of venous leg ulcer services: A willingness to pay study.Health science reports · 2022Article
- Evidence-Based Clinical Practice Points for the Management of Venous Ulcers.The Indian journal of surgery · 2018Review
- [Challenges of aging skin: Care and therapy using the example of venous ulcers].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2016Article
- Patients' perceptions and experiences of venous leg ulceration and their attitudes to larval therapy: an in-depth qualitative study.Health expectations : an international journal of public participation in health care and health policy · 2015Article
- Seeking effective interventions to treat complex wounds: an overview of systematic reviews.BMC medicine · 2015Review
- A comparison of the efficacy and cost of different venous leg ulcer dressings: a retrospective cohort study.International journal of vascular medicine · 2015Article
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo review the evidence of effectiveness of dressings applied to venous leg ulcers.
designSystematic review and meta-analysis. DATA SOURCES: Hand searches of journals and searches of electronic databases, conference proceedings, and bibliographies up to April 2006; contacts with dressing manufacturers for unpublished studies. STUDIES REVIEWED: All randomised controlled trials that evaluated dressings applied to venous leg ulcers were eligible for inclusion. Data from eligible studies were extracted and summarised independently by two reviewers using a data extraction sheet. Methodological quality was assessed independently by two reviewers.
resultsThe search strategy identified 254 studies; 42 of these fulfilled the inclusion criteria. Hydrocolloids were no more effective than simple low adherent dressings used beneath compression (eight trials; relative risk for healing with hydrocolloid 1.02, 95% confidence interval 0.83 to 1.28). For other comparisons, insufficient evidence was available to allow firm conclusions to be drawn. None of the dressing comparisons showed evidence that a particular class of dressing healed more ulcers. Some differences existed between dressings in terms of subjective outcome measures and ulcer healing rates. The results were not affected by the size or quality of trials or the unit of randomisation. Insufficient data were available to allow conclusions to be drawn about the relative cost effectiveness of different dressings.
conclusionsThe type of dressing applied beneath compression was not shown to affect ulcer healing. The results of the meta-analysis showed that applying hydrocolloid dressings beneath compression produced no benefit in terms of ulcer healing compared with applying simple low adherent dressings. No conclusive recommendations can be made as to which type of dressing is most cost effective. Decisions on which dressing to apply should be based on the local costs of dressings and the preferences of the practitioner or patient.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.