ArticleProceedings of the National Academy of Sciences of the United States of America1991
Uncoupling thermotolerance from the induction of heat shock proteins.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1991. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 95 citations in OpenAlex.
- Investigating genetic variability in Hsp70 gene-5'-fragment and its association with thermotolerance in Murrah buffalo (Bubalus bubalis) under sub-tropical climate of India.Cell stress & chaperones · 2020Article
- Roles of Three HSF Domain-Containing Proteins in Mediating Heat-Shock Protein Genes and Sustaining Asexual Cycle, Stress Tolerance, and Virulence inFrontiers in microbiology · 2018Article
- HSP70 as a marker of heat and humidity stress in Tarai buffalo.Tropical animal health and production · 2015Article
- Modelling the efficacy of hyperthermia treatment.Journal of the Royal Society, Interface · 2013Article
- Osmo-, Thermo- and Ethanol- Tolerances of Saccharomyces cerevisiae S1.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2012Article
- Heat shock proteins and resistance to desiccation in congeneric land snails.Cell stress & chaperones · 2010Article
- Effect of trehalose on protein structure.Protein science : a publication of the Protein Society · 2009Review
- Regulation of thermotolerance by stress-induced transcription factors in Saccharomyces cerevisiae.Eukaryotic cell · 2008Article
- Expression of heat shock protein 70 in the thermally stressed antarctic clam Laternula elliptica.Cell stress & chaperones · 2007Article
- Increased ubiquitin-dependent degradation can replace the essential requirement for heat shock protein induction.The EMBO journal · 2003Article
- Pleiotropic morphological and abiotic stress resistance phenotypes of the hyper-abscisic acid producing Abo- mutant in the periwinkle Catharanthus roseus.Journal of biosciences · 2001Article
- SSB, encoding a ribosome-associated chaperone, is coordinately regulated with ribosomal protein genes.Journal of bacteriology · 1999Article
- Proteasome inhibitors cause induction of heat shock proteins and trehalose, which together confer thermotolerance in Saccharomyces cerevisiae.Molecular and cellular biology · 1998Article
- Multiple functions of Drosophila heat shock transcription factor in vivo.The EMBO journal · 1997Article
- Heat-shock protein 104 expression is sufficient for thermotolerance in yeast.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- Oxidative stress is involved in heat-induced cell death in Saccharomyces cerevisiae.Proceedings of the National Academy of Sciences of the United States of America · 1996Article
- The Saccharomyces cerevisiae HSP12 gene is activated by the high-osmolarity glycerol pathway and negatively regulated by protein kinase A.Molecular and cellular biology · 1995Article
- Heat shock response and heat shock protein antigens of Vibrio cholerae.Infection and immunity · 1994Article
- Yap1p, a yeast transcriptional activator that mediates multidrug resistance, regulates the metabolic stress response.The EMBO journal · 1994Article
- A Saccharomyces cerevisiae UAS element controlled by protein kinase A activates transcription in response to a variety of stress conditions.The EMBO journal · 1993Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Exposure of cells to elevated temperatures causes a rapid increase in the synthesis of heat shock proteins (hsps) and induces thermotolerance, the increased ability of cells to survive exposure to lethal temperatures; however, the connection between hsp induction and the acquisition of thermotolerance is unclear. hsp induction in the yeast Saccharomyces cerevisiae is mediated by the activation of heat-shock transcription factor, and recently we have described a mutation, hsf1-m3, in heat-shock transcription factor that prevents the factor's activation. We now demonstrate that this mutation results in a general block in heat-shock induction but does not affect the acquisition of thermotolerance. Our results indicate that high-level induction of the major hsps is not required for cells to acquire thermotolerance.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.