Evidence map›Paper›PMID 17629910›Full record

ArticleBMC public health2007

Cohort differences in disease and disability in the young-old: findings from the MRC Cognitive Function and Ageing Study (MRC-CFAS).

Carol Jagger, Ruth J Matthews, Fiona E Matthews, Nicola A Spiers, Judith Nickson, Eugene S Paykel, Felicia A Huppert, Carol Brayne, Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS)

Abstract readComparative Study
In one paragraph

Article in BMC public health, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Are Advances in Survival Among the Oldest Old Seen Across the Spectrum of Health and Functioning?The journals of gerontology. Series A, Biological sciences and medical sciences · 2020
    Article
  5. Physical, sensory, and cognitive functioning among centenarians: a comparison between the Tokyo and Georgia centenarian studies.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Cognitive and physical functions as determinants of delayed age at onset and progression of disability.The journals of gerontology. Series A, Biological sciences and medical sciences · 2012
    Article
  11. Article
  12. Article
  13. Article
  14. Ageing populations: the challenges ahead.Lancet (London, England) · 2009
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Carol JaggerLeicester Nuffield Research Unit, Department of Health Sciences, University of Leicester, UK. cxj@leicester.ac.uk
Ruth J Matthews
Fiona E Matthews
Nicola A Spiers
Judith Nickson
Eugene S Paykel
Felicia A Huppert
Carol Brayne
Medical Research Council Cognitive Function and Ageing Study (MRC-CFAS)

Funding

Medical Research Council G9901400Medical Research Council MC_U105292687
6 · The paper itself

Abstract

backgroundProjections of health and social care need are highly sensitive to assumptions about cohort trends in health and disability. We use a repeated population-based cross-sectional study from the Cambridgeshire centre of the UK Medical Research Council Cognitive Function and Ageing Study to investigate trends in the health of the young-old UK population

methodsNon-overlapping cohorts of men and women aged 65-69 years in 1991/2 (n = 689) and 1996/7 (n = 687) were compared on: self-reported diseases and conditions; self-rated health; mobility limitation; disability by logistic regression and four-year survival by Cox Proportional Hazards Regression models, with adjustments for differences in socio-economic and lifestyle factors.

resultsSurvival was similar between cohorts (HR: 0.91, 95% CI: 0.62 to 1.32). There was a significant increase in the number of conditions reported between cohorts, with more participants reporting 3 or more conditions in the new cohort (14.2% vs. 10.1%). When individual conditions were considered, there was a 10% increase in the reporting of arthritis and a significant increase in the reporting of chronic airways obstruction (OR: 1.36, 95% CI: 1.04 to 1.78).

conclusionThis study provides evidence of rising levels of ill-health, as measured by the prevalence of self-reported chronic conditions, in the newer cohorts of the young-old. Though changes in diagnosis or reporting of disease cannot, as yet, be excluded, to better understand whether our findings reflect real increases in ill-health, investment should be made into improved population-based databases, linking self-report and objective measures of health and function, and including those in long-term care.

Indexed as

AgingHealth StatusAgedChronic DiseaseCognition DisordersCross-Sectional StudiesDisability EvaluationFemaleHumansLogistic ModelsMaleMiddle AgedPopulation SurveillanceProportional Hazards ModelsSurvival AnalysisUnited Kingdom

Identifiers

PMID17629910
PMCPMC1947964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.