ReviewParasitology research2007
Epidemiology, pathophysiology, management and outcome of renal dysfunction associated with plasmodia infection.
Review in Parasitology research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Clinical characteristics and outcome of malaria-associated acute kidney injury in adult patients: a systematic review and meta analysis.Malaria journal · 2026Pooled it
- UHPLC/MS Profile and Antimalarial Potency ofAdvances in pharmacological and pharmaceutical sciences · 2025Article
- Factors Associated with Acute Kidney Injury among Children with Severe Malaria at Kiryandongo General Hospital, Uganda.International journal of pediatrics · 2023Article
- Exploring the Role of Antioxidants to Combat Oxidative Stress in Malaria Parasites.Current topics in medicinal chemistry · 2022Article
- Evaluation of Antimalarial Potential of Extracts fromEvidence-based complementary and alternative medicine : eCAM · 2021Article
- Predictors of outcome in childhoodVirulence · 2020Review
- Evaluating the potential of using urine and saliva specimens for malaria diagnosis in suspected patients in Ghana.Malaria journal · 2020Article
- Kidney biomarkers in tropical infections: an update.Pathogens and global health · 2020Review
- Article
- Autoantibodies and Malaria: Where We Stand? Insights Into Pathogenesis and Protection.Frontiers in cellular and infection microbiology · 2020Review
- Novel kidney injury biomarkers in tropical infections: a review of the literature.Revista do Instituto de Medicina Tropical de Sao Paulo · 2020Review
- Mouse NC/Jic strain provides novel insights into host genetic factors for malaria research.Experimental animals · 2019Review
- Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice.Clinical and experimental nephrology · 2017Article
- The clinical and biochemical features of complicated falciparum malarial nephropathy.Journal of Taibah University Medical Sciences · 2017Article
- Kidney involvement in malaria: an update.Revista do Instituto de Medicina Tropical de Sao Paulo · 2017Review
- Delayed Diagnosis of Falciparum Malaria with Acute Kidney Injury.Journal of Korean medical science · 2016Article
- Depletion of Phagocytic Cells during Nonlethal Plasmodium yoelii Infection Causes Severe Malaria Characterized by Acute Renal Failure in Mice.Infection and immunity · 2016Article
- Why the communicable/non-communicable disease dichotomy is problematic for public health control strategies: implications of multimorbidity for health systems in an era of health transition.International health · 2015Review
- Protective Effect of Aqueous Crude Extract of Neem (Azadirachta indica) Leaves on Plasmodium berghei-Induced Renal Damage in Mice.Journal of tropical medicine · 2015Article
- High prevalence and genetic diversity of Plasmodium malariae and no evidence of Plasmodium knowlesi in Bangladesh.Parasitology research · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malaria remains a serious health problem in many parts of the world. It causes high morbidity and claims many lives in developing countries each year. Humans are generally infected by four species of malaria parasites. However, malaria infection caused by Plasmodium malariae or P. falciparum is recognized as an important cause of acute renal failure (ARF) and other renal-related disorders (nephropathy) in infected patients. The increasing incidence of malarial ARF (MARF) and the emergence of clinical malarial infection after renal transplantation represent a serious challenge. Additionally, the impact of immunosuppressive therapies on malarial infection is intricate, complex, and not yet well defined. Pathogenesis of MARF is most likely to be due to immune complex-mediated glomerulonephritis caused by immune-complex deposition and endothelial damage, which may lead to fatal forms of quartan malarial nephropathies. Effects of mechanical, immunologic, cytokine, humoral, acute phase response, and hemodynamics factors in inducing malarial nephropathy have also been postulated. Development of preventive strategies aimed at combating MARF and other renal disorders associated with malaria infection requires (1) prevention of malarial infection, (2) early diagnosis, and (3) early referral to well-equipped centers to provide renal replacement therapy, if necessary, along with antimalarial therapy and support. These measures could significantly reduce mortality and enhance recovery of renal function.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.