Evidence map›Paper›PMID 17628466›Full record

ReviewCurrent opinion in cell biology2007

Lysosome-related organelles: driving post-Golgi compartments into specialisation.

Graça Raposo, Michael S Marks, Daniel F Cutler

Abstract readReview
In one paragraph

Review in Current opinion in cell biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Skin lamellar bodies: a unique set of lysosome-related organelles.Frontiers in cell and developmental biology · 2025
    Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. RAB3A Regulates Melanin Exocytosis and Transfer Induced by Keratinocyte-Conditioned Medium.JID innovations : skin science from molecules to population health · 2022
    Article
  14. Article
  15. KIF13A-A Key Regulator of Recycling Endosome Dynamics.Frontiers in cell and developmental biology · 2022
    Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article

61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Graça RaposoInstitut Curie, Centre de Recherche, Paris F-75248, France. graca.roposo@curie.fr
Michael S Marks
Daniel F Cutler

Funding

Hermansky Pudlak Syndrome &melanosome formationR01EY015625 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Michael S Marks · 2004 to 2026
$9.2M
Melanosome BiogenesisR01AR048155 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI MARKS, MICHAEL S · 2002 to 2017
$4.2M
Medical Research Council MC_U122665003NEI NIH HHS R01 EY015625NIAMS NIH HHS R01 AR048155
6 · The paper itself

Abstract

Some cells harbour specialised lysosome-related organelles (LROs) that share features of late endosomes/lysosomes but are functionally, morphologically and/or compositionally distinct. Ubiquitous trafficking machineries cooperate with cell type specific cargoes to produce these organelles. Several genetic diseases are caused by dysfunctional LRO formation and/or motility. Many genes affected by these diseases have been recently identified, revealing new cellular components of the trafficking machinery. Current research reveals how the products of these genes cooperate to generate LROs and how these otherwise diverse organelles are related by the mechanisms through which they form.

Indexed as

Protein Sorting SignalsAnimalsCell CompartmentationEndosomesGolgi ApparatusHumansLysosomesMelanosomesOrganellesrab27 GTP-Binding Proteinsrab GTP-Binding ProteinsProtein Sorting SignalsRAB27A protein, humanrab27 GTP-Binding Proteinsrab GTP-Binding Proteins

Identifiers

PMID17628466
PMCPMC2782641

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.