Evidence map›Paper›PMID 17628132›Full record

ReviewMethods in enzymology2007

Comparative genomic and protein sequence analyses of a complex system controlling bacterial chemotaxis.

Kristin Wuichet, Roger P Alexander, Igor B Zhulin

Open access · greenAbstract readReview
In one paragraph

Review in Methods in enzymology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 80 papers.

0numbers the graph read from it
0cells of the map it votes in
80citing papers in PubMed
25.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

80 citing papers in PubMed, 129 citations in OpenAlex.

  1. ThemBio · 2026
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  13. Multistep Signaling in Nature: A Close-Up ofInternational journal of molecular sciences · 2021
    Review
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  15. Signs of biofilm formation in the genome ofSaudi journal of biological sciences · 2021
    Article
  16. Article
  17. Review on Stress Tolerance inFrontiers in cellular and infection microbiology · 2020
    Review
  18. Article
  19. Article
  20. Article

20 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kristin WuichetSchool of Biology, Georgia Institute of Technology, Atlanta, Georgia, USA.
Roger P Alexander
Igor B Zhulin
Georgia Institute of Technology · US

Funding

Computational Genomics of Signal TransductionR01GM072285 · NIGMS · UNIVERSITY OF TENNESSEE KNOXVILLE · PI JOULINE, IGOR B. · 2004 to 2018
$3.2M
NIGMS NIH HHS R01 GM072285
6 · The paper itself

Abstract

Molecular machinery governing bacterial chemotaxis consists of the CheA-CheY two-component system, an array of specialized chemoreceptors, and several auxiliary proteins. It has been studied extensively in Escherichia coli and, to a significantly lesser extent, in several other microbial species. Emerging evidence suggests that homologous signal transduction pathways regulate not only chemotaxis, but several other cellular functions in various bacterial species. The availability of genome sequence data for hundreds of organisms enables productive study of this system using comparative genomics and protein sequence analysis. This chapter describes advances in genomics of the chemotaxis signal transduction system, provides information on relevant bioinformatics tools and resources, and outlines approaches toward developing a computational framework for predicting important biological functions from raw genomic data based on available experimental evidence.

Indexed as

Bacterial ProteinsChemotaxisEscherichia coliEscherichia coli ProteinsGenetic VariationHistidine KinaseMembrane ProteinsMethyl-Accepting Chemotaxis ProteinsModels, MolecularProtein ConformationSignal TransductionBacterial ProteinscheA protein, E colicheY protein, E coliEscherichia coli ProteinsHistidine KinaseMembrane ProteinsMethyl-Accepting Chemotaxis Proteins

Identifiers

PMID17628132
PMCPMC2754700
OpenAlexW1570386349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.