Evidence map›Paper›PMID 17626158›Full record

ArticleClinical and vaccine immunology : CVI2007

Anti-16-kilodalton mycobacterial protein immunoglobulin m levels in healthy but purified protein derivative-reactive children decrease after chemoprophylaxis.

Guido Sireci, Francesco Dieli, Diana Di Liberto, Simona Buccheri, Marco Pio La Manna, Francesco Scarpa, Pasquale Macaluso, Amelia Romano, Lucina Titone, Paola Di Carlo and 3 more

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Guido SireciDipartimento di Biopatologia e Metodologie Biomediche, Università degli Studi di Palermo, Corso Tukory 211, 90100 Palermo, Italy. sireci@unipa.it
Francesco Dieli
Diana Di Liberto
Simona Buccheri
Marco Pio La Manna
Francesco Scarpa
Pasquale Macaluso
Amelia Romano
Lucina Titone
Paola Di Carlo
Mahavir Singh
Jurayi Ivanyi
Alfredo Salerno
Guy's Hospital · GBUniversity of Palermo · ITLionex (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum responses against Mycobacterium tuberculosis HSP16 were determined for children with tuberculosis (TB) and for healthy purified protein derivative (PPD)-positive and PPD-negative children. Immunoglobulin G (IgG) and IgM responses were higher for TB patients than for other groups. After chemotherapy, IgM and IgG responses decreased for TB patients and PPD-positive subjects. Monitoring of anti-M. tuberculosis HSP16 responses could assist in the management of pediatric TB.

Indexed as

AdolescentAntitubercular AgentsBacterial ProteinsChaperoninsChemopreventionChildChild, PreschoolEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin GImmunoglobulin MMycobacterium tuberculosisTuberculinTuberculosisAntitubercular AgentsBacterial ProteinsChaperoninsHsp16.3 protein, Mycobacterium tuberculosisImmunoglobulin GImmunoglobulin MTuberculin

Identifiers

PMID17626158
PMCPMC2043321
OpenAlexW2142372301

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.