Evidence map›Paper›PMID 17625571›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2007

Neonatal vitamin D status at birth at latitude 32 degrees 72': evidence of deficiency.

L A Basile, S N Taylor, C L Wagner, L Quinones, B W Hollis

Registry-linked trialAbstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00697294 (Vitamin D Status and Impact on Bone Mineralization in Human Milk Fed Hispanic and Caucasian Infants), which is not on this map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00697294 nacompletednot on this mapstarted 2008, after this paper: background citation

Vitamin D Status and Impact on Bone Mineralization in Human Milk Fed Hispanic and Caucasian Infants

TypeinterventionalSponsorBaylor College of MedicineRan2008 to 2011Enrolled80ConditionsVitamin D DeficiencyArmsTri-Vi-Sol
3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

L A BasileDivision of Neonatology, Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA.
S N Taylor
C L Wagner
L Quinones
B W Hollis

Funding

ZINC AND COPPER METABOLISM IN COLLAGEN DISORDERSM01RR001070 · NCRR · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI REVES, JOSEPH G · 1985 to 2009
$16.3M
Evaluation of Vitamin D Requirements During PregnancyR01HD043921 · NICHD · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI HOLLIS, BRUCE W · 2003 to 2007
$2.6M
NCRR NIH HHS RR01070NICHD NIH HHS 5R01HD043921-03
6 · The paper itself

Abstract

objectiveWith vitamin D deficiency as a serious public health problem, vitamin D status at birth was measured in neonates at latitude 32 degrees 72' (southeastern United States). STUDY

designIn umbilical cord blood, vitamin D status, demonstrated by circulating 25-hydroxyvitamin D, was measured and related to race and season of birth.

resultThe mean+/-standard deviation of 25-hydroxyvitamin D in 100 cord blood samples was 13.5+/-8.3 ng/ml for the cohort. African-American infants, with a mean+/-standard deviation of 10.5+/-6.0 ng/ml, demonstrated significantly lower vitamin D status than Caucasian infants, with a mean+/-standard deviation of 19.5+/-9.6 ng/ml (P<0.0001). By season, the mean 25-hydroxyvitamin D level at birth in November-March compared to April-October was 11.3 ng/ml lower in Caucasian infants (from 29.0 to 17.7 ng/ml) and 3 ng/ml lower in African-American infants (from 13.1 to 10.1 ng/ml).

conclusionThe prevalence of vitamin D insufficiency is high in this cohort. African-American infants demonstrate significantly lower vitamin D status at birth than Caucasian infants. Seasonality, while significant in both groups, had a greater impact on the vitamin D status of Caucasian newborns.

Indexed as

SeasonsBlack or African AmericanCohort StudiesCross-Sectional StudiesFemaleFetal BloodHumansHydroxycholecalciferolsInfant, NewbornMaleUnited StatesVitamin D DeficiencyWhite PeopleHydroxycholecalciferols

Identifiers

PMID17625571

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.