ReviewSeminars in immunopathology2007
Antisperm antibodies and conception.
Review in Seminars in immunopathology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 119 citations in OpenAlex.
- Urogenital Infection as a Risk Factor for Male Infertility.Deutsches Arzteblatt international · 2017Pooled it
- A versatile capsule-intravaginal ring platform enables rapid and sustained release of monoclonal antibodies for non-hormonal contraception.Journal of controlled release : official journal of the Controlled Release Society · 2026Article
- Non-hormonal Contraception: Current and Emerging Targets.Advances in experimental medicine and biology · 2025Review
- Advances in Male Contraception: When Will the Novel Male Contraception be Available?The world journal of men's health · 2024Review
- From Diagnosis to Treatment: Comprehensive Care by Reproductive Urologists in Assisted Reproductive Technology.Medicina (Kaunas, Lithuania) · 2023Review
- Regulatory T cells play a crucial role in maintaining sperm tolerance and male fertility.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- The impact of male factors and their correct and early diagnosis in the infertile couple's pathway: 2021 perspectives.Journal of endocrinological investigation · 2022Review
- Pathogenesis of Autoimmune Male Infertility: Juxtacrine, Paracrine, and Endocrine Dysregulation.Pathophysiology : the official journal of the International Society for Pathophysiology · 2021Review
- Potential mechanisms of SARS-CoV-2 action on male gonadal function and fertility: Current status and future prospects.Andrologia · 2021Review
- Review
- Human spermatozoa anti-proprotein convertase subtilisin/kexin type 4 synthesis using New Zealand rabbit for novel immunocontraception in males.Investigative and clinical urology · 2019Article
- An observational multicentre study on the efficacy and safety of assisted reproductive technologies in women with rheumatic diseases.Rheumatology advances in practice · 2019Article
- Intracytoplasmic sperm injection for male infertility and consequences for offspring.Nature reviews. Urology · 2018Review
- Infectious, inflammatory and 'autoimmune' male factor infertility: how do rodent models inform clinical practice?Human reproduction update · 2018Review
- Recombinant Human PH20: Baseline Analysis of the Reactive Antibody Prevalence in the General Population Using Healthy Subjects.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2018Article
- A Mouse Model for Dietary Xenosialitis: ANTIBODIES TO XENOGLYCAN CAN REDUCE FERTILITY.The Journal of biological chemistry · 2016Article
- The role of SPRASA in female fertility.Reproductive sciences (Thousand Oaks, Calif.) · 2015Article
- Quantification of anti-sperm antibody and soluble MICA/MICB levels in the serum of infertile people of the Li ethnic group in China.International journal of clinical and experimental medicine · 2015Article
- Prostasomes: Their Characterisation: Implications for Human Reproduction: Prostasomes and Human Reproduction.Advances in experimental medicine and biology · 2015Review
- Standardization of a method to detect bovine sperm-bound antisperm antibodies by flow cytometry.Theriogenology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sperm have been known to be antigenic for more than a century. There is a strong body of evidence that in humans and in other species at least some antibodies that bind to sperm antigens can cause infertility. Therefore, these antibodies are of interest today for two practical reasons. Firstly, the association of the antibodies with infertility means that they must be detected and then the couples treated appropriately. Secondly, because these antibodies can induce infertility they have the potential to be developed for contraceptive purposes in humans and also for the control of feral animal populations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.