Evidence map›Paper›PMID 17620378›Full record

ArticleAntimicrobial agents and chemotherapy2007

Treatment of a clinically relevant plant-pathogenic fungus with an agricultural azole causes cross-resistance to medical azoles and potentiates caspofungin efficacy.

Albrecht Serfling, Johannes Wohlrab, Holger B Deising

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 47 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Mechanisms and significance of fungicide resistance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2008
    Article
  12. Is the emergence of fungal resistance to medical triazoles related to their use in the agroecosystems? A mini review.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Albrecht SerflingFaculty of Agriculture, Institute of Agricultural and Nutritional Sciences, Phytopathology and Plant Protection, Martin Luther University Halle-Wittenberg, D-06099, Halle (Saale), Germany.
Johannes Wohlrab
Holger B Deising
Martin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Azoles are extensively applied in agriculture and medicine, and a relationship between the development of azole resistance in agriculture and the development of azole resistance in clinical practice may exist. The maize pathogen Colletotrichum graminicola, causing cutaneous mycosis and keratitis, has been used to investigate the acquisition of resistance to an agricultural azole and the resulting cross-resistance to various medical antifungal agents. Azole-adapted strains were less sensitive to all azoles tested but showed increased sensitivity to caspofungin, amphotericin B, and nystatin. Viability staining and infection assays with excised human skin confirmed these data.

Indexed as

Amphotericin BAntifungal AgentsAzolesCaspofunginColletotrichumDrug Resistance, FungalDrug SynergismEchinocandinsFungiFungicides, IndustrialHumansIn Vitro TechniquesLipopeptidesMicrobial Sensitivity TestsMicroscopy, FluorescenceNystatinAmphotericin BAntifungal AgentsAzolesCaspofunginEchinocandinsFungicides, IndustrialLipopeptidesNystatintebuconazoleTriazoles

Identifiers

PMID17620378
PMCPMC2043250
OpenAlexW2121070069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.