Evidence map›Paper›PMID 17620119›Full record

ArticleInfectious agents and cancer2007

Simian virus 40 in humans.

Fernanda Martini, Alfredo Corallini, Veronica Balatti, Silvia Sabbioni, Cecilia Pancaldi, Mauro Tognon

Abstract read
In one paragraph

Article in Infectious agents and cancer, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
  2. Establishment of a cell line from the hematophagous Bat Desmodus rotundus susceptible to Lyssavirus rabies.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  3. Review
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  6. The Wheel of p53 Helps to Drive the Immune System.International journal of molecular sciences · 2023
    Review
  7. Article
  8. Article
  9. Article
  10. Immortalization of primary sheep embryo kidney cells.In vitro cellular & developmental biology. Animal · 2021
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Serodiagnosis for tumor viruses.Seminars in oncology · 2015
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Fernanda MartiniDepartment of Morphology and Embryology, Section of Cell Biology and Molecular Genetics, School of Medicine, and Center of Biotechnology, University of Ferrara, Via Fossato di Mortara, 64/B, 44100 Ferrara, Italy. tgm@unife.it
Alfredo Corallini
Veronica Balatti
Silvia Sabbioni
Cecilia Pancaldi
Mauro Tognon

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Simian virus 40 (SV40) is a monkey virus that was administered to human populations by contaminated vaccines which were produced in SV40 naturally infected monkey cells. Recent molecular biology and epidemiological studies suggest that SV40 may be contagiously transmitted in humans by horizontal infection, independently from the earlier administration of SV40-contaminated vaccines.SV40 footprints in humans have been found associated at high prevalence with specific tumor types such as brain and bone tumors, mesotheliomas and lymphomas and with kidney diseases, and at lower prevalence in blood samples from healthy donors. Contrasting reports appeared in the literature on the circulation of SV40 in humans by contagious transmission and its association, as a possible etiologic cofactor, with specific human tumors. As a consequence of the conflicting results, a considerable debate has developed in the scientific community. In the present review we consider the main results obtained by different groups investigating SV40 sequences in human tumors and in blood specimens, the putative role of SV40 in the onset/progression of specific human tumors, and comment on the hypotheses arising from these data.

Identifiers

PMID17620119
PMCPMC1941725

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.