ArticleApplied and environmental microbiology2007
Emergence of a virulent clade of Vibrio vulnificus and correlation with the presence of a 33-kilobase genomic island.
Article in Applied and environmental microbiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
44 citing papers in PubMed, 85 citations in OpenAlex.
- Virulent properties and genomic diversity ofMicrobiology spectrum · 2024Article
- Prevalence, Genetic Diversity, Antimicrobial Resistance, and Toxigenic Profile ofAntibiotics (Basel, Switzerland) · 2021Article
- Phylogeography of the marine pathogen, Vibrio vulnificus, revealed the ancestral scenarios of its evolution.MicrobiologyOpen · 2020Article
- Article
- Whole-genome comparison between reference sequences and oyster Vibrio vulnificus C-genotype strains.PloS one · 2019Article
- Occurrence and significance of pathogenicity and fitness islands in environmental vibrios.AMB Express · 2018Article
- Environmental role of pathogenic traits inJournal of bacteriology · 2018Article
- Occurrence of clinical genotypeJournal of food science and technology · 2017Article
- MARTX Toxin in the Zoonotic Serovar ofFrontiers in cellular and infection microbiology · 2017Article
- Phylogeny ofFrontiers in microbiology · 2017Article
- Virulence Profiles of Vibrio vulnificus in German Coastal Waters, a Comparison of North Sea and Baltic Sea Isolates.International journal of environmental research and public health · 2015Article
- Clinical and environmental genotypes of Vibrio vulnificus display distinct, quorum-sensing-mediated, chitin detachment dynamics.Pathogens and disease · 2015Article
- Post-Genomic Analysis of Members of the Family Vibrionaceae.Microbiology spectrum · 2015Review
- Molecular and Physical Factors That Influence Attachment of Vibrio vulnificus to Chitin.Applied and environmental microbiology · 2015Article
- Populations, not clones, are the unit of vibrio pathogenesis in naturally infected oysters.The ISME journal · 2015Article
- Role of anaerobiosis in capsule production and biofilm formation in Vibrio vulnificus.Infection and immunity · 2015Article
- Article
- Vibrio vulnificus biotype 3 multifunctional autoprocessing RTX toxin is an adenylate cyclase toxin essential for virulence in mice.Infection and immunity · 2014Article
- Implications of chitin attachment for the environmental persistence and clinical nature of the human pathogen Vibrio vulnificus.Applied and environmental microbiology · 2014Article
- Genome-wide SNP-genotyping array to study the evolution of the human pathogen Vibrio vulnificus biotype 3.PloS one · 2014Article
Corrections and comments
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Authors and funding
5 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Vibrio vulnificus is a ubiquitous inhabitant of the marine coastal environment, and an important pathogen of humans. We characterized a globally distributed sample of environmental isolates from a range of habitats and hosts and compared these with isolates recovered from cases of human infection. Multilocus sequence typing data using six housekeeping genes divided 63 of the 67 isolates into the two main lineages previously noted for this species, and this division was also confirmed using the 16S rRNA and open reading frame VV0401 markers. Lineage I was comprised exclusively of biotype 1 isolates, whereas lineage II contained biotype 1 and all biotype 2 isolates. Four isolates did not cluster within either lineage: two biotype 3 and two biotype 1 isolates. The proportion of isolates recovered from a clinical setting was noted to be higher in lineage I than in lineage II. Lineage I isolates were also associated with a 33-kb genomic island (region XII), one of three regions identified by genome comparisons as unique to the species. Region XII contained an arylsulfatase gene cluster, a sulfate reduction system, two chondroitinase genes, and an oligopeptide ABC transport system, all of which are absent from the majority of lineage II isolates. Arylsulfatases and the sulfate reduction system, along with performing a scavenging role, have been hypothesized to play a role in pathogenic processes in other bacteria. Our data suggest that lineage I may have a higher pathogenic potential and that region XII, along with other regions, may give isolates a selective advantage either in the human host or in the aquatic environment or both.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.