Evidence map›Paper›PMID 17616603›Full record

ArticleJournal of bacteriology2007

Genetic code ambiguity confers a selective advantage on Acinetobacter baylyi.

Jamie M Bacher, William F Waas, David Metzgar, Valérie de Crécy-Lagard, Paul Schimmel

Abstract read
In one paragraph

Article in Journal of bacteriology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Bacterial translation machinery for deliberate mistranslation of the genetic code.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  7. The impact of mistranslation on phenotypic variability and fitness.Evolution; international journal of organic evolution · 2021
    Article
  8. Article
  9. Review
  10. Review
  11. Function and origin of mistranslation in distinct cellular contexts.Critical reviews in biochemistry and molecular biology · 2017
    Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jamie M BacherThe Scripps Research Institute, 10550 N. Torrey Pines Rd., BCC-379, La Jolla, CA 92037, USA.
William F Waas
David Metzgar
Valérie de Crécy-Lagard
Paul Schimmel

Funding

GENETIC APPROACHES TO PROTEIN/NUCLEIC ACID INTERACTIONSR01GM023562 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI SCHIMMEL, PAUL R · 1985 to 2012
$4.9M
NIGMS NIH HHS GM23562NIGMS NIH HHS R01 GM023562
6 · The paper itself

Abstract

A primitive genetic code, composed of a smaller set of amino acids, may have expanded via recursive periods of genetic code ambiguity that were followed by specificity. Here we model a step in this process by showing how genetic code ambiguity could result in an enhanced growth rate in Acinetobacter baylyi.

Indexed as

Genetic CodeAcinetobacter

Identifiers

PMID17616603
PMCPMC1951902

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.