Evidence map›Paper›PMID 17615907›Full record

ArticleJournal of health, population, and nutrition2007

Antimicrobial susceptibility patterns of Salmonella enterica serotype typhi in eastern Nepal.

Basudha Khanal, Sanjib Kumar Sharma, Shyamal Kumar Bhattacharya, Narayan Raj Bhattarai, Monorama Deb, Reba Kanungo

Open access · greenAbstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 50 citations in OpenAlex.

  1. Persistent febrile illnesses in Nepal: A systematic review.The Indian journal of medical research · 2018
    Pooled it
  2. Trial
  3. Article
  4. Frontiers in microbiology · 2023
    Article
  5. Article
  6. Antimicrobial Resistance in Typhoidal Salmonella: Surveillance for Enteric Fever in Asia Project, 2016-2019.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2020
    Article
  7. Article
  8. Article
  9. Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug Resistant Pathogens.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2017
    Article
  10. Renaissance of Conventional First-Line Antibiotics inBioMed research international · 2017
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Basudha KhanalDepartment of Microbiology, B.P. Koirala Institute of Health Sciences, Dharan, Nepal. basudhak@yahoo.com
Sanjib Kumar Sharma
Shyamal Kumar Bhattacharya
Narayan Raj Bhattarai
Monorama Deb
Reba Kanungo
B.P. Koirala Institute of Health Sciences · NP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to evaluate antimicrobial susceptibility patterns with special reference to multidrug resistance, susceptibility to ciprofloxacin, and bacteriophage typing of Salmonella enterica serotype Typhi isolated from blood sent for culture in a tertiary-care teaching hospital in eastern Nepal during January 2000-December 2004. In total, 132 strains of S. enterica Typhi, isolated from 2,568 blood culture samples collected from cases of suspected enteric fever, were tested for susceptibility to commonly-used antimicrobials by the disc-diffusion method. There were 35 multidrug-resistant strains. None of the isolates were resistant to ciprofloxacin. Of 52 isolates tested for minimum inhibitory concentration (MIC) of ciprofloxacin, 36 (69.23%) showed reduced susceptibility (MIC >0.25 mg/L). Of 112 strains tested for nalidixic acid susceptibility, 86 (76%) were resistant. Strains with reduced susceptibility to ciprofloxacin and resistance to nalidixic acid could be correlated. The commonest phage type was El. Nalidixic acid susceptibility could be a useful screening test for the detection of decreased susceptibility of S. Typhi to ciprofloxacin, a drug which is commonly used even for minor ailments in this area.

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsCiprofloxacinColony Count, MicrobialDose-Response Relationship, DrugDrug Resistance, Multiple, BacterialHumansMicrobial Sensitivity TestsNalidixic AcidNepalSalmonella typhiTyphoid FeverAnti-Bacterial AgentsCiprofloxacinNalidixic Acid

Identifiers

PMID17615907
PMCPMC3013267
OpenAlexW1823793377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.