ReviewThe AAPS journal2007
Nanosystems for simultaneous imaging and drug delivery to T cells.
Review in The AAPS journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed.
- An Evaluation of the Potential Radiosensitization Effect of Spherical Gold Nanoparticles to Induce Cellular Damage Using Different Radiation Qualities.Molecules (Basel, Switzerland) · 2025Article
- Therapeutic Potential of Nanocarriers in the Management of Rheumatoid Arthritis.Current rheumatology reviews · 2025Review
- Nanoparticle-Based Drug Delivery for Vascular Applications.Bioengineering (Basel, Switzerland) · 2024Review
- Nano-delivery systems as a promising therapeutic potential for epilepsy: Current status and future perspectives.CNS neuroscience & therapeutics · 2023Review
- Transnasal-brain delivery of nanomedicines for neurodegenerative diseases.Frontiers in drug delivery · 2023Review
- Effects of Lipid Shape and Interactions on the Conformation, Dynamics, and Curvature of Ultrasound-Responsive Liposomes.Pharmaceutics · 2022Article
- Biomolecular engineering of drugs loading in Riboflavin-targeted polymeric devices: simulation and experimental.Scientific reports · 2022Article
- The Emerging Role of Ultrasonic Nanotechnology for Diagnosing and Treatment of Diseases.Frontiers in medicine · 2022Review
- In Situ Programming of CAR T Cells.Annual review of biomedical engineering · 2021Review
- Moderate Static Magnetic Field (6 mT)-Induced Lipid Rafts Rearrangement Increases Silver NPs Uptake in Human Lymphocytes.Molecules (Basel, Switzerland) · 2020Article
- Biocompatible Polymer Nanoparticles for Drug Delivery Applications in Cancer and Neurodegenerative Disorder Therapies.Journal of functional biomaterials · 2019Review
- Pharmaceutical Approaches to HIV Treatment and Prevention.Advanced therapeutics · 2018Article
- Precision DNA demethylation ameliorates disease in lupus-prone mice.JCI insight · 2018Article
- Nanotheranostics - application and further development of nanomedicine strategies for advanced theranostics.Theranostics · 2014Review
- Microfluidics-assisted in vitro drug screening and carrier production.Advanced drug delivery reviews · 2013Review
- Analysis of the murine immune response to pulmonary delivery of precisely fabricated nano- and microscale particles.PloS one · 2013Article
- The dendritic cell response to classic, emerging, and homeostatic danger signals. Implications for autoimmunity.Frontiers in immunology · 2013Article
- Article
- Polymeric nanoparticles for drug delivery to the central nervous system.Advanced drug delivery reviews · 2012Review
- Enhancement of surface ligand display on PLGA nanoparticles with amphiphilic ligand conjugates.Journal of controlled release : official journal of the Controlled Release Society · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The T-cell response defines the pathogenesis of many common chronic disease states, including diabetes, rheumatoid arthritis, and transplant rejection. Therefore, a diagnostic strategy that visualizes this response can potentially lead to early therapeutic intervention, avoiding catastrophic organ failure or prolonged sickness. In addition, the means to deliver a drug dose to those cells in situ with the same specificity used to image those cells would provide for a powerful therapeutic alternative for many disease states involving T cells. In this report, we review emerging nanosystems that can be used for simultaneous tracking and drug delivery to those cells. Because of their versatility, these systems--which combine specific receptor targeting with an imaging agent and drug delivery--are suited to both basic science and applications, from developing therapeutic strategies for autoimmune and alloimmune diseases, to noninvasive tracking of pathogenic T-cell migration.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.