ArticleOrigins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life2007
Question 6: coevolution theory of the genetic code: a proven theory.
Article in Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- The Role of Mutations, Addition of Amino Acids, and Exchange of Genetic Information in the Coevolution of Primitive Coding Systems.International journal of molecular sciences · 2025Article
- The influence of different types of translational inaccuracies on the genetic code structure.BMC bioinformatics · 2019Article
- Future of the Genetic Code.Life (Basel, Switzerland) · 2017Review
- Coevolution Theory of the Genetic Code at Age Forty: Pathway to Translation and Synthetic Life.Life (Basel, Switzerland) · 2016Article
- How amino acids and peptides shaped the RNA world.Life (Basel, Switzerland) · 2015Review
- A realistic model under which the genetic code is optimal.Journal of molecular evolution · 2013Article
- The scenario on the origin of translation in the RNA world: in principle of replication parsimony.Biology direct · 2010Article
- Article
- Exceptional error minimization in putative primordial genetic codes.Biology direct · 2009Article
- Optimization models and the structure of the genetic code.Journal of molecular evolution · 2009Review
- Origin and evolution of the genetic code: the universal enigma.IUBMB life · 2009Review
- The capabilities of chaos and complexity.International journal of molecular sciences · 2009Review
- Aminoacylation of tRNA with phosphoserine for synthesis of cysteinyl-tRNA(Cys).Nature structural & molecular biology · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The coevolution theory proposes that primordial proteins consisted only of those amino acids readily obtainable from the prebiotic environment, representing about half the twenty encoded amino acids of today, and the missing amino acids entered the system as the code expanded along with pathways of amino acid biosynthesis. The isolation of genetic code mutants, and the antiquity of pretran synthesis revealed by the comparative genomics of tRNAs and aminoacyl-tRNA synthetases, have combined to provide a rigorous proof of the four fundamental tenets of the theory, thus solving the riddle of the structure of the universal genetic code.
Indexed as
Identifiers
17611816What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.