Evidence map›Paper›PMID 17611716›Full record

ReviewJournal of neuro-oncology2008

A case of 'lymphomatosis cerebri' diagnosed in an early phase and treated by whole brain radiation: case report and literature review.

Ryuichi Kanai, Makoto Shibuya, Takashi Hata, Makoto Hori, Kenichi Hirabayashi, Tadashi Terada, Koji Fujii

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Journal of neuro-oncology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Diffuse leukoencephalopathy due to lymphomatosis cerebri: a clinicopathological report.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2015
    Article
  8. Neurocognitive features distinguishing primary central nervous system lymphoma from other possible causes of rapidly progressive dementia.Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology · 2015
    Article
  9. Lymphomatosis cerebri: a treatable cause of rapidly progressive dementia.Journal of neurology, neurosurgery, and psychiatry · 2015
    Article
  10. Lymphomatosis cerebri.Journal of Korean Neurosurgical Society · 2013
    Article
  11. Article
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Ryuichi KanaiDepartment of Neurosurgery, Shizuoka City Shimizu Hospital, Shizuoka, Japan. ryuichi@kj9.so-net.ne.jp
Makoto Shibuya
Takashi Hata
Makoto Hori
Kenichi Hirabayashi
Tadashi Terada
Koji Fujii
Shizuoka City Shimizu Hospital · JPShizuoka City Hospital · JPTokai University · JPTokyo Medical University Hachioji Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

'Lymphomatosis cerebri' (LC) is a term indicating a diffusely infiltrating form of primary central nervous system lymphoma (PCNSL) without evidence of a mass lesion. Not infrequently, diagnostic confusion is caused by its presentation on cranial magnetic resonance images (MRI), which is characterized by diffuse leukoencephalopathy without contrast enhancement. In this report, we describe a 53-year-old, immunocompetent man who had an insidiously progressive dementia and right weakness. On serial MRI in 4 months duration, diffuse white matter lesions without contrast enhancement gradually progressed, which was clinically consistent with his worsening condition. Biopsy specimen demonstrated nondestructive, diffusely infiltrating, large B-cell lymphoma, diagnosing LC. After the biopsy, corticosteroids were initiated, which dramatically alleviated his symptoms. Afterwards, he was treated by whole brain irradiation (total 36Gy) and discharged without noticeable deficits. Diagnosis of LC requires additional examinations generally not performed in the other white matter disorders. In suspected cases, biopsy should be performed to avoid deferring adequate cytostatic treatment.

Indexed as

BrainBrain NeoplasmsHumansLymphomaMaleMiddle Aged

Identifiers

PMID17611716
OpenAlexW2166745945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.