ArticleBMC musculoskeletal disorders2007
50 years experience with Dupuytren's contracture in the Erlangen University Hospital--a retrospective analysis of 2919 operated hands from 1956 to 2006.
Article in BMC musculoskeletal disorders, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 110 citations in OpenAlex.
- Handchirurgie, Mikrochirurgie, plastische Chirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Handchirurgie : Organ der Deutschsprachigen Arbeitsgemeinschaft fur Mikrochirurgie der Peripheren Nerven und Gefasse : Organ der V... · 2026Review
- A Personalized Approach to Treat Advanced Stage Severely Contracted Joints in Dupuytren's Disease with a Unique Skeletal Distraction Device-Utilizing Modern Imaging Tools to Enhance Safety for the Patient.Journal of personalized medicine · 2022Article
- Treatment Options for Dupuytren's Disease: Tips and Tricks.Plastic and reconstructive surgery. Global open · 2022Review
- Establishing Age-calibrated Normative PROMIS Scores for Hand and Upper Extremity Clinic.Plastic and reconstructive surgery. Global open · 2021Article
- Hand disorders demographics in rural areas: A 15-year analysis of demographic characteristics overtime in a stable population.Acta orthopaedica et traumatologica turcica · 2020Article
- Percutaneous needle fasciotomy in Dupuytren contracture: a register-based, observational cohort study on complications in 3,331 treated fingers in 2,257 patients.Acta orthopaedica · 2020Observational
- Feasibility analysis of conducting observational studies with the electronic health record.BMC medical informatics and decision making · 2019Article
- [Epidemiology of Dupuytren's disease].Der Orthopade · 2017Review
- Collagenase Treatment in Dupuytren Contractures: A Review of the Current State Versus Future Needs.Rheumatology and therapy · 2016Review
- Clinical outcomes following collagenase injections compared to fasciectomy in the treatment of Dupuytren's contracture.Hand (New York, N.Y.) · 2015Article
- Epidemiological profile of Dupuytren's disease in Taiwan (Ethnic Chinese): a nationwide population-based study.BMC musculoskeletal disorders · 2015Article
- Safety and tolerability of collagenase Clostridium histolyticum and fasciectomy for Dupuytren's contracture.The Journal of hand surgery, European volume · 2015Review
- Postapproval clinical experience in the treatment of Dupuytren's contracture with collagenase clostridium histolyticum (CCH): the first 1,000 days.Hand (New York, N.Y.) · 2014Review
- Surgical treatment of Dupuytren's disease - outcome and health economy in relation to smoking and diabetes.BMC musculoskeletal disorders · 2014Article
- Eliciting health state utilities for Dupuytren's contracture using a discrete choice experiment.Acta orthopaedica · 2013Article
- Prevalence of hand disorders in type 2 diabetes mellitus and its correlation with microvascular complications.Annals of medical and health sciences research · 2013Article
- Current trends in the surgical management of Dupuytren's disease in Europe: an analysis of patient charts.European orthopaedics and traumatology · 2012Article
- Dupuytren's Contracture in Alabama HFE Hemochromatosis Probands.Clinical medicine insights. Arthritis and musculoskeletal disorders · 2012Article
- Prevalence, incidence, and treatments of Dupuytren's disease in the United States: results from a population-based study.Hand (New York, N.Y.) · 2011Article
- Dupuytren's contracture: a retrospective database analysis to assess clinical management and costs in England.BMC musculoskeletal disorders · 2011Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDupuytren's disease (DD) is a hand disorder mainly among the northern population. In contrast it is rare in the mediterranean population. Therefore typical habits and dietetic influences have been discussed as well as genetic predisposition. Still, since the first description by Dupuytren in 1834 only little is known about the etiology and pathogenesis of this disease. Some hints were found for a higher prevalence among people with diabetes, alcohol abuse or smoking. Also, intensive manual work or hand injuries have been discussed to have an influence on DD. To our knowledge this is the largest retrospectively evaluated series of symptomatic patients published to date. The study includes patients from the last 50 years. It was performed to show possible correlations between DD and typical risk factors such as diabetes, alcohol consumption, and smoking.
methodsWe retrospectively analysed all patient records with DD documented between 1956 and 2006 in the Surgical University Hospital in Erlangen. Data acquisition was conducted by reviewing the medical records from 1956 to 2006 including data from all patients who were surgically treated because of DD.
resultsWe reviewed 2579 male and 340 female surgically treated patients with DD. More than 80% of the patients were between 40 and 70 years old. In 28.9% only the right hand was effected by DD, in 25.3% only the left hand and in 45.8% both hands. In 10.3% of all Patients suffered from Diabetes mellitus. Statistical analysis revealed no significant correlation between diabetes, alcoholism or smoking on the degree of DD in our patients.
conclusionMost data are consistent with previously published results from smaller, comparable retrospective studies with regard to right- or left handedness. We could not confirm a statistically significant correlation of DD with diabetes mellitus, severe alcohol consumption, heavy smoking or epilepsy and the stage of the disease as described in other studies. However, in the whole cohort of our operated patients during the last 50 years the prevalence of the above mentioned risk factors is slightly higher than in the normal population.
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