ReviewInternational orthopaedics2007
Biological mechanisms of bone and cartilage remodelling--genomic perspective.
Review in International orthopaedics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
33 citing papers in PubMed, 43 citations in OpenAlex.
- Correlation between synovial fluid and serum IL-1beta levels after ACL surgery-preliminary report.International orthopaedics · 2009Trial
- Wnt Signaling Inhibitors and Their Promising Role in Tumor Treatment.International journal of molecular sciences · 2023Review
- Bisphenol A Represses Dopaminergic Neuron Differentiation from Human Embryonic Stem Cells through Downregulating the Expression of Insulin-like Growth Factor 1.Molecular neurobiology · 2017Article
- Evaluation of fibrin-based gene-activated matrices for BMP2/7 plasmid codelivery in a rat nonunion model.International orthopaedics · 2014Article
- Nonviral gene transfer to human meniscal cells. Part I: transfection analyses and cell transplantation to meniscus explants.International orthopaedics · 2014Article
- Bone marrow derived stem cells in joint and bone diseases: a concise review.International orthopaedics · 2014Review
- Osteoporosis and the orthopaedic surgeon: basic concepts for successful co-management of patients' bone health.International orthopaedics · 2014Review
- Apolipoprotein E gene E2/E2 genotype is a genetic risk factor for vertebral fractures in humans: a large-scale study.International orthopaedics · 2014Article
- The effect of platelet-rich plasma on osteochondral defects treated with mosaicplasty.International orthopaedics · 2014Article
- The clinical use of bone morphogenetic proteins revisited: a novel biocompatible carrier device OSTEOGROW for bone healing.International orthopaedics · 2014Review
- Abnormal expression of chondroitin sulphate N-acetylgalactosaminyltransferase 1 and Hapln-1 in cartilage with Kashin-Beck disease and primary osteoarthritis.International orthopaedics · 2013Article
- Cell biology of osteochondromas: bone morphogenic protein signalling and heparan sulphates.International orthopaedics · 2013Review
- In vitro hypertrophy and calcification of human fracture haematoma-derived cells in chondrogenic differentiation.International orthopaedics · 2013Article
- Article
- Comparative characteristics of porous bioceramics for an osteogenic response in vitro and in vivo.PloS one · 2013Article
- Cysteine-rich matricellular protein improves callus regenerate in a rabbit trauma model.International orthopaedics · 2012Article
- Potential of exogenous cartilage proteoglycan as a new material for cartilage regeneration.International orthopaedics · 2012Article
- A novel recirculating flow-perfusion bioreactor for periosteal chondrogenesis.International orthopaedics · 2012Article
- Effect of rat brain tissue extracts on osteoblast proliferation and differentiation.International orthopaedics · 2012Article
- Dual function of β-catenin in articular cartilage growth and degeneration at different stages of postnatal cartilage development.International orthopaedics · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Rapid advancements in the field of genomics, enabled by the achievements of the Human Genome Project and the complete decoding of the human genome, have opened an unimaginable set of opportunities for scientists to further unveil delicate mechanisms underlying the functional homeostasis of biological systems. The trend of applying whole-genome analysis techniques has also contributed to a better understanding of physiological and pathological processes involved in homeostasis of bone and cartilage tissues. Gene expression profiling studies have yielded novel insights into the complex interplay of osteoblast and osteoclast regulation, as well as paracrine and endocrine control of bone and cartilage remodelling. Mechanisms of new bone formation responsible for fracture healing and distraction osteogenesis, as well as healing of joint cartilage defects, have also been extensively studied. Microarray experiments have been especially useful in studying pathological processes involved in diseases such as osteoporosis or bone tumours. Existing results show that microarrays hold great promise in areas such as identification of targets for novel therapies or development of new biomarkers and classifiers in skeletal diseases.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.