Trial reportUrological research2007
The use of tamsulozin as adjunctive treatment after ESWL in patients with distal ureteral stone: do we really need it? Results from a randomised study.
Trial report in Urological research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- Alpha-blockers after shock wave lithotripsy for renal or ureteral stones in adults.The Cochrane database of systematic reviews · 2020Pooled it
- Is tamsulosin effective for the passage of symptomatic ureteral stones: A systematic review and meta-analysis.Medicine · 2019Pooled it
- Comparative efficacy of tamsulosin versus nifedipine for distal ureteral calculi: a meta-analysis.Drug design, development and therapy · 2016Pooled it
- Adjunctive medical therapy with α-blocker after extracorporeal shock wave lithotripsy of renal and ureteral stones: a meta-analysis.PloS one · 2015Pooled it
- A comparison of nifedipine and tamsulosin as medical expulsive therapy for the management of lower ureteral stones without ESWL.Scientific reports · 2014Pooled it
- Stone expulsion rate of small distal ureteric calculi could be predicted with plasma C-reactive protein.Urolithiasis · 2013Trial
- Tamsulosin and doxazosin as adjunctive therapy following shock-wave lithotripsy of renal calculi: randomized controlled trial.Urological research · 2012Trial
- Article
- A network meta-analysis on the beneficial effect of medical expulsive therapy after extracorporeal shock wave lithotripsy.Scientific reports · 2017Article
- Medical expulsive treatment in pediatric urolithiasis.Turkish journal of urology · 2015Review
- The efficacy of tamsulosin therapy after extracorporeal shock-wave lithotripsy for ureteric calculi: A prospective randomised, controlled study.Arab journal of urology · 2013Article
- The effect of tamsulosin on pain and clearance according to ureteral stone location after shock wave lithotripsy.Current therapeutic research, clinical and experimental · 2013Article
- Efficacy of alfuzosin after shock wave lithotripsy for the treatment of ureteral calculi.Korean journal of urology · 2013Article
- Optimizing shock wave lithotripsy: a comprehensive review.Reviews in urology · 2013Article
- Review
- Does tamsulosin facilitate expulsion of distal ureteric calculus following lithotripsy?Indian journal of urology : IJU : journal of the Urological Society of India · 2008Article
- CUA Guideline: Management of ureteral calculi.Canadian Urological Association journal = Journal de l'Association des urologues du CanadaArticle
- A novel triple oral regime provides effective analgesia during extracorporeal shockwave lithotripsy for renal stones.Urology annalsArticle
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Our study aimed to define the position of tamsulosin as adjunctive therapy in patients with stones of the distal ureter who had undergone extracorporeal shock wave lithotripsy (ESWL). In total, 61 consecutive patients (38 men and 23 women) with single distal radiopaque ureteral stone of > or =6 mm of diameter were enrolled. After ESWL patients were randomized in two groups. Non-steroidal anti-inflammatory drug (supp. diclofenac 50 mg) was given to both groups upon demand. In group B, all patients (30) received additionally tamsulozin 0.4 mg every day. Follow-up visits were performed 1, 2, 3 and 4 weeks after ESWL. Evaluation included a KUB plain film and an ultrasound examination. Efficacy was evaluated in terms of success rate, stone-free rate, expulsion time of the fragments and use of diclofenac. Two patients from the tamsulosin group experienced dizziness and one was withdrawn. The success rate was 58.06 and 66.66% for the control and the tamsulosin group, respectively, while the corresponding values for stone-free rate were 51.6 and 63.33%, respectively. The mean expulsion time of the fragments was 13.22 days for group A and 12.95 days for group B. These results did not achieve statistically significant difference (P > 0.05). The mean diclofenac dose was 118.9 mg in group A and 56.9 mg in group B. This difference was statistically significant (P = 0.02). Despite the relatively small number of patients, our data indicate that the use of tamsulosin after ESWL in this specific subgroup of patients does not result in improved success and stone-free rate and expulsion time. In contrast, a significantly reduced need for analgesics was found.
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