Evidence map›Paper›PMID 17607348›Full record

ReviewThe Journal of clinical investigation2007

Genomics and the evolution, pathogenesis, and diagnosis of tuberculosis.

Joel D Ernst, Giraldina Trevejo-Nuñez, Niaz Banaiee

Abstract readReview
In one paragraph

Review in The Journal of clinical investigation, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
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  5. Article
  6. Article
  7. Article
  8. Immunogenicity of heparin-binding hemagglutinin expressed byIranian journal of basic medical sciences · 2018
    Article
  9. Novel polymorphisms inGlobal health, epidemiology and genomics · 2018
    Article
  10. Comparative Proteomics Analysis of Human Macrophages Infected with VirulentFrontiers in cellular and infection microbiology · 2017
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joel D ErnstDepartment of Medicine, Division of Infectious Diseases, New York University School of Medicine, New York, NY 10016, USA. joel.ernst@med.nyu.edu
Giraldina Trevejo-Nuñez
Niaz Banaiee

Funding

Initiation of the Immune Response to M. tuberculosisR01AI051242 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ERNST, JOEL D. · 2002 to 2019
$8.3M
M TUBERCULOSIS EVASION OF IMMUNE EFFECTOR MECHANISMSR01AI046097 · NIAID · UNIVERSITY OF CALIFORNIA SAN FRANCISCO · PI ERNST, JOEL D. · 2000 to 2008
$3.8M
Type I Interferons in Immunity to TuberculosisR01AI059667 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ERNST, JOEL D. · 2004 to 2008
$2.0M
Identification/Characterization of M. tuberculosis GenesK08AI061105 · NIAID · STANFORD UNIVERSITY · PI BANAIEE, NIAZ · 2004 to 2007
$498k
NIAID NIH HHS K08 AI061105NIAID NIH HHS R01 AI046097NIAID NIH HHS R01 AI051242NIAID NIH HHS R01 AI059667NIAID NIH HHS R01 AI59667
6 · The paper itself

Abstract

Tuberculosis kills nearly 2 million people annually, and current approaches to tuberculosis control are expensive, have limited efficacy, and are vulnerable to being overcome by extensively drug-resistant strains of Mycobacterium tuberculosis. Determination of the genome sequence of M. tuberculosis has revolutionized tuberculosis research, contributed to major advances in the understanding of the evolution and pathogenesis of M. tuberculosis, and facilitated development of new diagnostic tests with increased specificity for tuberculosis. In this review, we describe some of the major progress in tuberculosis research that has resulted from knowledge of the genome sequence and note some of the problems that remain unsolved.

Indexed as

Biological EvolutionGenomicsAnimalsBacterial ProteinsHomeodomain ProteinsHumansMycobacterium tuberculosisTuberculosisBacterial ProteinsHomeodomain Proteins

Identifiers

PMID17607348
PMCPMC1904327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.