ArticleCMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne2007
Rate of methadone use among Aboriginal opioid injection drug users.
Article in CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 17 citations in OpenAlex.
- Future directions for medication assisted treatment for opioid use disorder with American Indian/Alaska Natives.Addictive behaviors · 2018Article
- Impact of binge alcohol on mortality among people who inject drugs.Addictive behaviors reports · 2015Article
- The impact of drug use patterns on mortality among polysubstance users in a Canadian setting: a prospective cohort study.BMC public health · 2014Article
- Offending, custody and opioid substitution therapy treatment utilisation among opioid-dependent people in contact with the criminal justice system: comparison of Indigenous and non-Indigenous Australians.BMC public health · 2014Article
- Injection drug use cessation and use of North America's first medically supervised safer injecting facility.Drug and alcohol dependence · 2011Article
- Inability to access addiction treatment and risk of HIV infection among injection drug users recruited from a supervised injection facility.Journal of public health (Oxford, England) · 2010Article
- Methadone use among HIV-positive injection drug users in a Canadian setting.Journal of substance abuse treatment · 2010Article
- Ethnic disparities in accessing treatment for depression and substance use disorders in an integrated health plan.International journal of psychiatry in medicine · 2010Article
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Authors and funding
6 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies have shown elevated rates of health-related harms among Aboriginal people who use injection drugs such as heroin. Methadone maintenance therapy is one of the most effective interventions to address the harms of heroin injection. We assessed the rate of methadone use in a cohort of opioid injection drug users in Vancouver and investigated whether methadone use was associated with Aboriginal ethnic background.
methodsUsing data collected as part of the Vancouver Injection Drug Users Study (May 1996-November 2005), we evaluated whether Aboriginal ethnic background was associated with methadone use using generalized estimating equations and Cox regression analysis. We compared methadone use among Aboriginal and non-Aboriginal injection drug users at the time of enrollment and during the follow-up period, and we evaluated the time to first methadone use among people not using methadone at enrollment.
resultsDuring the study period, 1603 injection drug users (435 Aboriginal, 1168 non-Aboriginal) were recruited. At enrollment, 54 (12.4%) Aboriginal participants used methadone compared with 247 (21.2%) non-Aboriginal participants (odds ratio [OR] 0.53, 95% confidence interval [CI] 0.38-0.73, p < 0.001). Among the 1351 (84.3%) participants who used heroin, Aboriginal people were less likely to use methadone throughout the follow-up period (adjusted OR 0.60, 95% CI 0.45-0.81, p < 0.001). Among people using heroin but who were not taking methadone at enrollment, Aboriginal ethnic background was associated with increased time to first methadone use (adjusted relative hazard 0.60, 95% CI 0.49-0.74, p < 0.001).
interpretationMethadone use was lower among Aboriginal than among non-Aboriginal injection drug users. Culturally appropriate interventions with full participation of the affected community are required to address this disparity.
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