ArticleProceedings of the National Academy of Sciences of the United States of America2007
Corticothalamic synchronization leads to c-fos expression in the auditory thalamus.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 26 citations in OpenAlex.
- Recovery of Retinal Terminal Fields after Traumatic Brain Injury: Evidence of Collateral Sprouting and Sexual Dimorphism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Recovery of retinal terminal fields after traumatic brain injury: evidence of collateral sprouting and sexual dimorphism.bioRxiv : the preprint server for biology · 2025Article
- Attenuating midline thalamus bursting to mitigate absence epilepsy.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Characterization of the neural circuitry of the auditory thalamic reticular nucleus and its potential role in salicylate-induced tinnitus.Frontiers in neuroscience · 2024Article
- Activation of prefrontal cortex and striatal regions in rats after shifting between rules in a T-maze.Learning & memory (Cold Spring Harbor, N.Y.) · 2023Article
- Physical exercise promotes integration of grafted cells and functional recovery in an acute stroke rat model.Stem cell reports · 2022Article
- Daily and Estral Regulation of RFRP-3 Neurons in the Female Mice.Journal of circadian rhythms · 2021Article
- Top-Down Inference in the Auditory System: Potential Roles for Corticofugal Projections.Frontiers in neural circuits · 2020Review
- Neuronal networks and mediators of cortical neurovascular coupling responses in normal and altered brain states.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2016Review
- Orexin Neurons Respond Differentially to Auditory Cues Associated with Appetitive versus Aversive Outcomes.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- The effect of music performance on the transcriptome of professional musicians.Scientific reports · 2015Article
- Across-ear stimulus-specific adaptation in the auditory cortex.Frontiers in neural circuits · 2014Article
- Pyramidal neurons are "neurogenic hubs" in the neurovascular coupling response to whisker stimulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Article
- Change detection by thalamic reticular neurons.Nature neuroscience · 2009Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, we investigated the relationship between c-fos expression in the auditory thalamus and corticofugal activation. The contribution of neurotransmitters and related receptors, the involvement of thalamic reticular nucleus (TRN), and the role of neuronal firing patterns in this process were also examined. The principal nuclei of the medial geniculate body (MGB) showed c-fos expression when the auditory cortex (AC) was activated by direct injection of bicuculline methobromide. However, no expression was detectable with acoustic stimuli alone. This indicated that c-fos expression in the principal nuclei of the MGB was triggered by the corticofugal projection. c-fos expression could be elicited in the MGB by direct injection of glutamate. Direct administration of acetylcholine, alternatively, had no effect. Bicuculline methobromide injection in the AC also triggered synchronized oscillatory activities sequentially in the AC and MGB. Cortically induced c-fos expression in the MGB was not mediated by a pathway involving the TRN because it remained intact after a TRN lesion with kainic acid. The present results also conclude that c-fos expression is not simply associated with firing rate, but also with neuronal firing pattern. Burst firings that are synchronized with the cortical oscillations are proposed to lead to c-fos expression in the principal nuclei of the MGB.
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