ArticleProceedings of the National Academy of Sciences of the United States of America2007
Identification of a fourth family of lycopene cyclases in photosynthetic bacteria.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers.
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Who cites it
51 citing papers in PubMed, 96 citations in OpenAlex.
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- Structure and regulation of violaxanthin de-epoxidase, a key enzyme in the photoprotection of photosynthesis.Plant physiology · 2026Review
- Distribution, Biosynthesis, and Function of Carotenoids in Oxygenic Phototrophic Algae.Marine drugs · 2025Review
- Genetic and biochemical diversity of terpene biosynthesis in cyanobacterial strains from tropical soda lakes.Frontiers in microbiology · 2025Article
- GhLCYε-3 characterized as a lycopene cyclase gene responding to drought stress in cotton.Computational and structural biotechnology journal · 2024Article
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- Enhancement of β-carotene content in Chlamydomonas reinhardtii by expressing bacterium-driven lycopene β-cyclase.Biotechnology for biofuels and bioproducts · 2023Article
- Overexpressing Carotenoid Biosynthetic Genes inInternational journal of molecular sciences · 2023Article
- Absolute quantification of cellular levels of photosynthesis-related proteins in Synechocystis sp. PCC 6803.Photosynthesis research · 2023Article
- Comparative Genomic Analysis ofMicroorganisms · 2023Article
- Comparative genomic insights into habitat adaptation of coral-associatedFrontiers in microbiology · 2023Article
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- Genome Sequence and Characterization of a Xanthorhodopsin-Containing, Aerobic Anoxygenic PhototrophicMicroorganisms · 2022Article
- Coenzyme BEnvironmental microbiology · 2022Article
- Carotenoid biomarkers in Namibian shelf sediments: Anoxygenic photosynthesis during sulfide eruptions in the Benguela Upwelling System.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Introduction of the Carotenoid Biosynthesis α-Branch IntoFrontiers in plant science · 2021Article
- Suppression of the Lycopene Cyclase Gene Causes Downregulation of Ascorbate Peroxidase Activity and Decreased Glutathione Pool Size, Leading to HFrontiers in plant science · 2021Article
- Diversity and Evolution of Carotenoid Biosynthesis from Prokaryotes to Plants.Advances in experimental medicine and biology · 2021Review
- Niche expansion for phototrophic sulfur bacteria at the Proterozoic-Phanerozoic transition.Proceedings of the National Academy of Sciences of the United States of America · 2020Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A fourth and large family of lycopene cyclases was identified in photosynthetic prokaryotes. The first member of this family, encoded by the cruA gene of the green sulfur bacterium Chlorobium tepidum, was identified in a complementation assay with a lycopene-producing strain of Escherichia coli. Orthologs of cruA are found in all available green sulfur bacterial genomes and in all cyanobacterial genomes that lack genes encoding CrtL- or CrtY-type lycopene cyclases. The cyanobacterium Synechococcus sp. PCC 7002 has two homologs of CruA, denoted CruA and CruP, and both were shown to have lycopene cyclase activity. Although all characterized lycopene cyclases in plants are CrtL-type proteins, genes orthologous to cruP also occur in plant genomes. The CruA- and CruP-type carotenoid cyclases are members of the FixC dehydrogenase superfamily and are distantly related to CrtL- and CrtY-type lycopene cyclases. Identification of these cyclases fills a major gap in the carotenoid biosynthetic pathways of green sulfur bacteria and cyanobacteria.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.