Evidence map›Paper›PMID 17603386›Full record

Trial reportClinical orthopaedics and related research2007

Pain and depression influence outcome 5 years after knee replacement surgery.

Victoria Brander, Stephen Gondek, Emily Martin, S David Stulberg

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Clinical orthopaedics and related research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06099223 (Open-Label Randomized Controlled Trial to Assess Preoperative Acupuncture for Patients Undergoing Total Knee or Hip Arthroplasty), which is not on this map. Cited by 122 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06099223 nacompletednot on this mapstarted 2022, after this paper: background citation

Open-Label Randomized Controlled Trial to Assess Preoperative Acupuncture for Patients Undergoing Total Knee or Hip Arthroplasty

TypeinterventionalSponsorHartford HospitalRan2022 to 2023Enrolled60ConditionsKnee Arthropathy, Hip Arthropathy, AnxietyArmsAcupuncture needles
3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  7. No clinical benefit of titanium nitride coating in cementless mobile-bearing total knee arthroplasty.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2015
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  10. The unhappy total knee arthroplasty (TKA) patient: higher WOMAC and lower KSS in depressed patients prior and after TKA.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2013
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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Victoria BranderNorthwestern University Feinberg School of Medicine, Northwestern Orthopedic Institute, Chicago, IL 60611, USA. victoriabrander@aol.com
Stephen Gondek
Emily Martin
S David Stulberg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledWe previously reported preoperative depression, anxiety, and pain were associated with greater pain, more utilization of healthcare resources, and worse outcome 1 year after total knee arthroplasty. We asked whether these outcomes persisted over time and whether patients with unexplained heightened pain early after surgery were ultimately satisfied. We prospectively followed and evaluated 83 patients (109 TKAs) 5 years postoperative. The mean age was 66 years; 55% were women. Preoperative pain and depression predicted lower Knee Society score mostly related to lower function subscores. Although anxiety was associated with greater pain, worse function, and more use of resources in the first year after surgery, anxiety did not affect ultimate outcome. Most patients required a full year to recover from surgery but with negligible improvements in most parameters afterward. However, patients with heightened, unexplained pain at 1 year had progressive improvement in pain over several years. By 5 years, nearly all of these patients were satisfied. Therefore, assuming good range of motion and well-aligned implants, most patients with pain 1 year after surgery can be reassured pain ultimately improves. Depression drives long-term outcomes; the Knee Society score is influenced by psychologic variables and does not solely reflect issues related to the knee. Expansion of this tool to include measures sensitive to psychologic and other health factors should be considered. LEVEL OF EVIDENCE: Level I, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.

Indexed as

AdultAgedAged, 80 and overAnxietyArthroplasty, Replacement, KneeDepressive DisorderFemaleFollow-Up StudiesHumansMaleMiddle AgedPatient SatisfactionPostoperative PainPrognosisProspective StudiesRange of Motion, Articular

Identifiers

PMID17603386

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.