ReviewCurrent cardiology reports2007
Pulmonary insufficiency is the nexus of late complications in tetralogy of Fallot.
Review in Current cardiology reports, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 30 citations in OpenAlex.
- Percutaneous Pulmonary Valve Implantation In Native Right Ventricular Outflow Tract Using Myval™ Without Pre-Stenting.Health science reports · 2025Article
- Early-term results of percutaneous pulmonary valve implantation (valve-in-valve) in dysfunctional bioprosthetic valves in pulmonary position.Turk gogus kalp damar cerrahisi dergisi · 2025Article
- β2-Adrenoceptors and GRK2 as Potential Biomarkers in Patients With Chronic Pulmonary Regurgitation.Frontiers in pharmacology · 2019Article
- Fibroblasts and the extracellular matrix in right ventricular disease.Cardiovascular research · 2017Review
- miR-21 is associated with fibrosis and right ventricular failure.JCI insight · 2017Article
- Implantation of the Medtronic Harmony Transcatheter Pulmonary Valve Improves Right Ventricular Size and Function in an Ovine Model of Postoperative Chronic Pulmonary Insufficiency.Circulation. Cardiovascular interventions · 2016Article
- Right Ventricular Apical Flattening as an Echocardiographic Screening Tool for Right Ventricular Enlargement.Pediatric cardiology · 2016Article
- Is Biventricular Fibrosis the Mediator of Late Complications in Tetralogy of Fallot?JACC. Cardiovascular imaging · 2016Article
- Physiologic and molecular characterization of a murine model of right ventricular volume overload.American journal of physiology. Heart and circulatory physiology · 2013Article
- Diastolic dysfunction: a new additional criterion for optimal timing of pulmonary valve replacement in adult patient with tetralogy of Fallot?The international journal of cardiovascular imaging · 2008Article
- Midgestation fetal pulmonary annulus size is predictive of outcome in tetralogy of fallot.Congenital heart diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The number of adults with tetralogy of Fallot now exceeds the number of children with the disorder due to childhood surgical successes. After surgical repair, however, most patients are left with pulmonary regurgitation that, over time, results in right ventricular volume overload, enlargement, and dysfunction. Usually well tolerated for 20 years or more, ongoing pulmonary insufficiency is at the core of late complications that include right ventricular failure, exercise intolerance, atrial and ventricular arrhythmias, and sudden death. Though late pulmonary valve replacement appears to attenuate this risk, prostheses have a finite life span. Thus, the timing of surgery must be carefully considered, weighing the up-front risks of surgery and possible repeat surgery against the risk of ongoing pulmonary regurgitation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.