ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2007
Magnetic resonance imaging of myelin.
Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 154 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
154 citing papers in PubMed, 2 syntheses or guidelines pooled it, 322 citations in OpenAlex.
- Intensity scaling of conventional brain magnetic resonance images avoiding cerebral reference regions: A systematic review.PloS one · 2024Pooled it
- Pooled it
- Effects of iron repletion on brain iron content, myelination, neural network activation, and cognition.JCI insight · 2025Trial
- MWF of the corpus callosum is a robust measure of remyelination: Results from the ReBUILD trial.Proceedings of the National Academy of Sciences of the United States of America · 2023Trial
- Limited Contribution of TMolecular imaging and biology · 2026Article
- Field Strength-Dependent White Matter RMagnetic resonance in medicine · 2026Article
- MC BTS: Simultaneously Resolving Magnetization Transfer Effect and Relaxation for Multiple Components.Magnetic resonance in medicine · 2026Article
- Neurorestorative properties of ibogaine: linking multi-receptor affinities to remyelination and metabolic restoration.Acta neuropsychiatrica · 2026Review
- Three-Dimensional Efficient Myelin-Weighted Imaging Utilizing Direct Visualization of Short Transverse Relaxation Time Component (ViSTa).Human brain mapping · 2025Article
- Brain short TNeuroImage · 2025Article
- Reversible reduction in brain myelin content upon marathon running.Nature metabolism · 2025Observational
- Myelin water fraction mapping with joint inversion of gradient-echo and spin-echo data.Magma (New York, N.Y.) · 2025Article
- Decoding Brain Development and Aging: Pioneering Insights From MRI Techniques.Investigative radiology · 2025Review
- An unconstrained four pool model analysis of proton relaxation and magnetization transfer in ex vivo white matter.Scientific reports · 2025Article
- White matter microstructure of language pathways in non-verbal autism: insights from diffusion tensor imaging and myelin water imaging.Frontiers in human neuroscience · 2025Article
- Brain microstructure alterations in subjective cognitive decline: a multi-component T2 relaxometry study.Brain communications · 2025Article
- Approximating R1 and R2: A Quantitative Approach to Clinical Weighted MRI.Human brain mapping · 2024Article
- Water phase transition and signal nulling in 3D dual-echo adiabatic inversion-recovery UTE (IR-UTE) imaging of myelin.Magnetic resonance in medicine · 2024Article
- Susceptibility-induced internal gradients reveal axon morphology and cause anisotropic effects in the diffusion-weighted MRI signal.Scientific reports · 2024Article
- Advanced MRI Measures of Myelin and Axon Volume Identify Repair in Multiple Sclerosis.Annals of neurology · 2024Article
94 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to measure myelin in vivo has great consequences for furthering our knowledge of normal development, as well as for understanding a wide range of neurological disorders. The following review summarizes the current state of myelin imaging using MR. We consider five MR techniques that have been used to study myelin: 1) conventional MR, 2) MR spectroscopy, 3) diffusion, 4) magnetization transfer, and 5) T2 relaxation. Fundamental studies involving peripheral nerve and MR/histology comparisons have aided in the interpretation and validation of MR data. We highlight a number of important findings related to myelin development, damage, and repair, and we conclude with a critical summary of the current techniques available and their potential to image myelin in vivo.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.