Evidence map›Paper›PMID 17599701›Full record

ReviewNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics2007

Clinical neuroimaging using arterial spin-labeled perfusion magnetic resonance imaging.

Ronald L Wolf, John A Detre

Abstract readReview
In one paragraph

Review in Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

85 citing papers in PubMed.

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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Ronald L WolfDepartment of Radiology, University of Pennsylvania Medical Center, Philadelphia, Pennsylvania 19104, USA. Ronald.Wolf@uphs.upenn.edu
John A Detre

Funding

WORKSHOP ON ADVANCES IN MUSCULOSKELETAL MRIP41RR002305 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI SONG, HEE KWON · 1985 to 2011
$14.7M
statistics coreP30NS045839 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DETRE, JOHN A · 2003 to 2017
$10.1M
Research Methods for Cognitive RehabilitationR24HD050836 · NICHD · ALBERT EINSTEIN HEALTHCARE NETWORK · PI WHYTE, JOHN · 2005 to 2009
$4.4M
Assessing Microstructure of Carotid Disease with MRI/MRSK23NS043381 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI WOLF, RONALD L · 2002 to 2006
$863k
NCRR NIH HHS RR002305NICHD NIH HHS HD050836NINDS NIH HHS K23 NS043381NINDS NIH HHS K23 NS43381NINDS NIH HHS P30 NS045839
6 · The paper itself

Abstract

The two most common methods for measuring perfusion with MRI are based on dynamic susceptibility contrast (DSC) and arterial spin labeling (ASL). Although clinical experience to date is much more extensive with DSC perfusion MRI, ASL methods offer several advantages. The primary advantages are that completely noninvasive absolute cerebral blood flow (CBF) measurements are possible with relative insensitivity to permeability, and that multiple repeated measurements can be obtained to evaluate one or more interventions or to perform perfusion-based functional MRI. ASL perfusion and perfusion-based functional MRI methods have been applied in many clinical settings, including acute and chronic cerebrovascular disease, CNS neoplasms, epilepsy, aging and development, neurodegenerative disorders, and neuropsychiatric diseases. Recent technical advances have improved the sensitivity of ASL perfusion MRI, and increasing use is expected in the coming years. The present review focuses on ASL perfusion MRI and applications in clinical neuroimaging.

Indexed as

Imaging, Three-DimensionalMagnetic Resonance ImagingBrainHumansSpin LabelsSpin Labels

Identifiers

PMID17599701
PMCPMC2031222

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.