ArticleInternational journal for parasitology2007
Density-dependent immune responses against the gastrointestinal nematode Strongyloides ratti.
Article in International journal for parasitology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
25 citing papers in PubMed, 70 citations in OpenAlex.
- Does vitamin A supplementation protect schoolchildren from acquiring soil-transmitted helminthiasis? A randomized controlled trial.Parasites & vectors · 2014Trial
- The effect of different intensities of the ectoparasitic salmon lice (Lepeophtheirus salmonis) on Atlantic salmon (Salmo salar).Journal of fish diseases · 2022Article
- Vaccine-induced time- and age-dependent mucosal immunity to gastrointestinal parasite infection.NPJ vaccines · 2022Article
- Within-host mechanisms of immune regulation explain the contrasting dynamics of two helminth species in both single and dual infections.PLoS computational biology · 2020Article
- Complex relationships between physiological stress and endoparasite infections in natural populations.Current zoology · 2020Article
- Ecological, parasitological and individual determinants of plasma neopterin levels in a natural mandrill population.International journal for parasitology. Parasites and wildlife · 2020Article
- External disturbances impact helminth-host interactions by affecting dynamics of infection, parasite traits, and host immune responses.Ecology and evolution · 2019Article
- Genotypic variation in parasite avoidance behaviour and other mechanistic, nonlinear components of transmission.Proceedings. Biological sciences · 2019Article
- Changes in parasite traits, rather than intensity, affect the dynamics of infection under external perturbation.PLoS computational biology · 2018Article
- Breaking beta: deconstructing the parasite transmission function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2017Article
- Strongyloides ratti and S. venezuelensis - rodent models of Strongyloides infection.Parasitology · 2017Review
- Germline organization in Strongyloides nematodes reveals alternative differentiation and regulation mechanisms.Chromosoma · 2016Article
- The influence of trematode parasite burden on gene expression in a mammalian host.BMC genomics · 2016Article
- Haemonchus contortus excretory and secretory proteins (HcESPs) suppress functions of goat PBMCs in vitro.Oncotarget · 2016Article
- Differential chromatin amplification and chromosome complements in the germline of Strongyloididae (Nematoda).Chromosoma · 2016Article
- Evaluation of biochemical, hematological and parasitological parameters of protein-deficient hamsters infected with Ancylostoma ceylanicum.PLoS neglected tropical diseases · 2014Article
- Density related effects on lifetime fecundity of Heterakis gallinarum in chickens.Parasites & vectors · 2014Article
- Innate and adaptive immunity to the nematode Strongyloides stercoralis in a mouse model.Immunologic research · 2011Review
- Neutrophil and eosinophil chemotactic factors in the excretory/secretory products of sheep abomasal nematode parasites: NCF and ECF in abomasal nematodes.Parasitology research · 2011Article
- Update on strongyloidiasis in the immunocompromised host.Current infectious disease reports · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
Abstract
Negative density-dependent effects on the fitness of parasite populations are an important force in their population dynamics. For the parasitic nematode Strongyloides ratti, density-dependent fitness effects require the rat host immune response. By analysis of both measurements of components of parasite fitness and of the host immune response to different doses of S. ratti infection, we have identified specific parts of the host immune response underlying the negative density-dependent effects on the fitness of S. ratti. The host immune response changes both qualitatively from an inflammatory Th1- to a Th2-type immune profile and the Th2-type response increases quantitatively, as the density of S. ratti infection increases. Parasite survivorship was significantly negatively related to the concentration of parasite-specific IgG(1) and IgA, whereas parasite fecundity was significantly negatively related to the concentration of IgA only.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.