Evidence map›Paper›PMID 17596977›Full record

ReviewSeminars in cell & developmental biology2007

Potassium channels and uterine function.

Adam M Brainard, Victoria P Korovkina, Sarah K England

Abstract readReview
In one paragraph

Review in Seminars in cell & developmental biology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
54citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

54 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adam M BrainardUniversity of Iowa Carver College of Medicine, Department of Molecular Physiology and Biophysics, Iowa City, IA 52242, United States.
Victoria P Korovkina
Sarah K England

Funding

REGULATION OF UTERINE SMOOTH MUSCLE EXCITABILITYR01HD037831 · NICHD · WASHINGTON UNIVERSITY · PI ENGLAND, SARAH K. · 1999 to 2023
$7.0M
NICHD NIH HHS HD-037831NICHD NIH HHS R01 HD037831
6 · The paper itself

Abstract

Ion channels are effector proteins that mediate uterine excitability throughout gestation. This review will focus primarily on the role of potassium channels in regulating myometrial tone in pregnancy and labor contractions. During gestation, potassium channels maintain the uterus in a state of quiescence by contributing to the resting membrane potential and counteracting contractile stimuli. This review summarizes the current knowledge about the significance of the potassium channels in maintaining a normal gestational period and initiating labor contractions at term.

Indexed as

Uterine ContractionAnimalsFemaleHumansIon ChannelsMyometriumPotassium ChannelsPregnancyIon ChannelsPotassium Channels

Identifiers

PMID17596977
PMCPMC2012947

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.