ArticleProceedings of the National Academy of Sciences of the United States of America2007
Conserved noncoding genomic sequences associated with a flowering-time quantitative trait locus in maize.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 308 papers, 1 of them a synthesis that pooled it.
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Who cites it
308 citing papers in PubMed, 1 synthesis or guideline pooled it, 620 citations in OpenAlex.
- Pooled it
- The MexMAGIC population reveals the genetic architecture of traits exhibiting clinal variation in Mexican native maize.The New phytologist · 2026Article
- Multimodal single cell analysis reveals a link between flowering and leaf initiation.bioRxiv : the preprint server for biology · 2026Article
- Structural Variation and Its Roles in Plant Genomes.Plants (Basel, Switzerland) · 2026Review
- Positional grammar of transcription factor binding partitions developmental and stress-response regulation in plants.Nature communications · 2026Article
- Designed Alleles of ZmRap2.7 Decouple the Trade-Off Between Early Flowering and Yield Penalty.Plant biotechnology journal · 2026Article
- Phenomics-derived temporal maize health and environmental index enhance physiology-informed genomic prediction of yield across environments.Plant physiology · 2026Article
- Global genetic dissection of maize-teosinte divergence reveals EL3-2 as a pleiotropic domestication regulator.Genome biology · 2026Article
- Power-law penalties correct distance bias in single-cell co-accessibility and deep-learning chromatin interaction predictions.NAR genomics and bioinformatics · 2026Article
- Targeted knockout of a host peroxisomal peptidase confers field resistance to maize lethal necrosis.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Dynamic and cell-type specific transcriptional reprogramming underlies the floral transition in the maize shoot apical meristem.Genome biology · 2026Article
- Integrated GWAS and Fst analysis identify flowering-time regulatory genes in maize.The plant genome · 2026Article
- Transposable element-mediated DNA methylation of the NAC20 and NAC26 promoters led to a maternal effect on grain filling.Journal of integrative plant biology · 2026Article
- A Trypsin-Like Serine Protease ZmNAL1a Fine-Tunes Maize Floral Transition and Flowering Time.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Plant domestication revisited: Genomic insights into origins, mechanisms, and convergent evolution.iScience · 2026Review
- Unlocking tropical adaptation: novel flowering time genes implicate JA and ROS signaling in maize.BMC plant biology · 2026Article
- The science and legacies of Ronald Phillips: A brief perspective.The plant genome · 2025Article
- Decades' progress and prospects on maize functional genomics and molecular breeding.Science China. Life sciences · 2025Review
- Plant MITEs: miniature transposable elements with major impacts.Mobile DNA · 2025Review
- Vegetative to generative1 (Vgt1) is an enhancer affecting flowering time and jasmonate signaling in maize by promoting the expression of Zea mays Related to APETALA 2.7.Plant physiology · 2025Article
248 more citing papers are in PubMed but not listed here.
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Authors and funding
19 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Flowering time is a fundamental trait of maize adaptation to different agricultural environments. Although a large body of information is available on the map position of quantitative trait loci for flowering time, little is known about the molecular basis of quantitative trait loci. Through positional cloning and association mapping, we resolved the major flowering-time quantitative trait locus, Vegetative to generative transition 1 (Vgt1), to an approximately 2-kb noncoding region positioned 70 kb upstream of an Ap2-like transcription factor that we have shown to be involved in flowering-time control. Vgt1 functions as a cis-acting regulatory element as indicated by the correlation of the Vgt1 alleles with the transcript expression levels of the downstream gene. Additionally, within Vgt1, we identified evolutionarily conserved noncoding sequences across the maize-sorghum-rice lineages. Our results support the notion that changes in distant cis-acting regulatory regions are a key component of plant genetic adaptation throughout breeding and evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.