ArticleNeurochemical research2008
Protective effects of resveratrol on hydrogen peroxide induced toxicity in primary cortical astrocyte cultures.
Article in Neurochemical research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
24 citing papers in PubMed.
- Methylprednisolone Induces Neuro-Protective Effects via the Inhibition of A1 Astrocyte Activation in Traumatic Spinal Cord Injury Mouse Models.Frontiers in neuroscience · 2021Article
- Functional Group-Dependent Induction of Astrocytogenesis and Neurogenesis by Flavone Derivatives.Biomolecules · 2019Article
- The Good, the Bad, and the Ugly of ROS: New Insights on Aging and Aging-Related Diseases from Eukaryotic and Prokaryotic Model Organisms.Oxidative medicine and cellular longevity · 2018Review
- Resveratrol Protects Hippocampal Astrocytes Against LPS-Induced Neurotoxicity Through HO-1, p38 and ERK Pathways.Neurochemical research · 2015Article
- Suppressive Effects of Resveratrol Treatment on The Intrinsic Evoked Excitability of CA1 Pyramidal Neurons.Cell journal · 2015Article
- High glutamate attenuates S100B and LDH outputs from rat cortical slices enhanced by either oxygen-glucose deprivation or menadione.Neurochemical research · 2014Article
- Resveratrol protects C6 astrocyte cell line against hydrogen peroxide-induced oxidative stress through heme oxygenase 1.PloS one · 2013Article
- Specific Conditions for Resveratrol Neuroprotection against Ethanol-Induced Toxicity.Journal of toxicology · 2012Article
- Resveratrol prevents ammonia toxicity in astroglial cells.PloS one · 2012Article
- Oil palm vegetation liquor: a new source of phenolic bioactives.The British journal of nutrition · 2011Article
- Hesperidin, a flavone glycoside, as mediator of neuronal survival.Neurochemical research · 2011Article
- Exacerbation of tobacco smoke mediated apoptosis by resveratrol: an unexpected consequence of its antioxidant action.The international journal of biochemistry & cell biology · 2011Article
- Pathways for ischemic cytoprotection: role of sirtuins in caloric restriction, resveratrol, and ischemic preconditioning.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2011Review
- In vitro and in vivo studies on stilbene analogs as potential treatment agents for colon cancer.European journal of medicinal chemistry · 2010Article
- Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death.Free radical biology & medicine · 2010Article
- Flavonoids and astrocytes crosstalking: implications for brain development and pathology.Neurochemical research · 2010Review
- trans-Resveratrol as a neuroprotectant.Molecules (Basel, Switzerland) · 2010Review
- Dietary restriction and brain health.Neuroscience bulletin · 2010Review
- Stroke status evoked adhesion molecule genetic alterations in astrocytes isolated from stroke-prone spontaneously hypertensive rats and the apigenin inhibition of their expression.Stroke research and treatment · 2010Article
- The janus face of resveratrol in astroglial cells.Neurotoxicity research · 2009Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
It is well established that the brain is particularly susceptible to oxidative damage due to its high consumption of oxygen and that astrocytes are involved in a variety of important activities for the nervous system, including a protective role against damage induced by reactive oxygen species (ROS). The use of antioxidant compounds, such as polyphenol resveratrol found in red wine, to improve endogenous antioxidant defenses has been proposed for neural protection. The aim of this study is to evaluate the putative protective effect of resveratrol against acute H2O2-induced oxidative stress in astrocyte cultures, evaluating ROS production, glutamate uptake activity, glutathione content and S100B secretion. Our results confirm the ability of resveratrol to counteract oxidative damage caused by H2O2, not only by its antioxidant properties, but also through the modulation of important glial functions, particularly improving glutamate uptake activity, increasing glutathione content and stimulating S100B secretion, which all contribute to the functional recovery after brain injury.
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17594518What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.