ArticleNeuroradiology2007
Fungal versus bacterial brain abscesses: is diffusion-weighted MR imaging a useful tool in the differential diagnosis?
Article in Neuroradiology, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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20 citing papers in PubMed, 59 citations in OpenAlex.
- Intraventricular black fungal hyphal masses caused by Cladophialophora bantiana: illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- MRI-based radiomics-deep learning model for preoperative pathogen prediction in perianal abscesses.Frontiers in medicine · 2026Article
- Cerebral Aspergillosis: Diagnostic Challenges, Therapeutic Strategies, and Future Research.CNS drugs · 2026Review
- Cerebritis, optic ischemia, and cavernous sinus thrombosis arising from sinonasal mucormycosis.Radiology case reports · 2024Article
- Radiological differentiation between bacterial orbital cellulitis and invasive fungal sino-orbital infections.International ophthalmology · 2024Article
- Evolution of neuroimaging findings in angioinvasive cerebral aspergillosis in a pediatric patient with leukemia during long-term observation.BMC infectious diseases · 2023Article
- Article
- AcuteInfection and drug resistance · 2023Article
- Clinical applications of diffusion-weighted sequence in brain imaging: beyond stroke.Neuroradiology · 2022Review
- Concomitant extradural, subdural, and intraparenchymal abscesses of the brain in a patient with cerebral melioidosis - A case report.Surgical neurology international · 2022Article
- Fungal infections in pediatric neurosurgery.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2018Review
- Role of diffusion-weighted imaging in skull base lesions: A pictorial review.The neuroradiology journal · 2017Review
- Pyogenic brain abscess with atypical features resembling glioblastoma in advanced MRI imaging.Radiology case reports · 2017Article
- Atypical pyogenic brain abscess evaluation by diffusion-weighted imaging: diagnosis with multimodality MR imaging.Japanese journal of radiology · 2015Article
- Psoas Abscess Secondary to Urinary Tract Fungal Infection.Urology case reports · 2015Article
- Differentiation of pyogenic and fungal brain abscesses with susceptibility-weighted MR sequences.Neuroradiology · 2014Article
- Neurocandidiasis: a case report and consideration of the causes of restricted diffusion.Journal of radiology case reports · 2013Article
- MRI-DWI improves the early diagnosis of brain abscess induced by Candida albicans in preterm infants.Translational pediatrics · 2012Article
- A new era in neuroradiology: ex vivo validation of in vivo imaging research.AJNR. American journal of neuroradiology · 2008Article
- Clinical Presentation and Outcome of Children with Brain Abscess.Annals of Indian Academy of NeurologyArticle
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of this study was to investigate the appearance of fungal brain abscesses on diffusion-weighted (DW) images, and to evaluate whether the imaging characteristics and apparent diffusion coefficient (ADC) values associated with fungal abscesses were distinct from those of bacterial abscesses.
methodsWe retrospectively reviewed the MR images from nine patients with fungal brain infections, and 17 patients with pyogenic brain abscesses. All patients underwent conventional MR sequences and DW imaging on 1.5-T clinical MR scanners. ADC values of 20 fungal and 20 bacterial brain abscesses were calculated and compared using a random factor analysis of variance.
resultsMultiple lesions were present in 6 of 9 patients (67%) with fungal abscesses and in 5 of 17 patients (29%) with bacterial abscesses. On DW images, all but one bacterial brain abscess showed a homogeneous high signal, whereas the appearance of fungal abscesses on DW images was more variable: in five of nine patients with fungal abscesses, the lesions were homogeneously hyperintense, while in the remaining four patients, the lesions were of mixed signal intensity. Mean ADC values were 0.74 x 10(-3) mm(2)/s in the fungal group and 0.486 x 10(-3) mm(2)/s in the bacterial group (P< or =0.05).
conclusionOur results indicate that there is a trend towards higher ADC values in fungal lesions. Additional findings that support fungal rather than bacterial cerebral infection are multiplicity, signal heterogeneity on T2-weighted and DW imaging, and involvement of deep grey-matter nuclei.
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