ReviewClinical research in cardiology : official journal of the German Cardiac Society2007
Treatment of hypertension in patients with diabetes mellitus : relevance of sympathovagal balance and renal function.
Review in Clinical research in cardiology : official journal of the German Cardiac Society, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed, 16 citations in OpenAlex.
- Angiotensin II, sympathetic nerve activity and chronic heart failure.Heart failure reviews · 2014Review
- Beneficial effect of calcium channel blockers on home blood pressure variability in the morning in patients with type 2 diabetes.Journal of diabetes investigation · 2013Article
- Cardiovascular autonomic response to amlodipine in primary hypertension.ISRN cardiology · 2012Article
- Screening for undiagnosed diabetes in patients with acute myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2008Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 2 countries.
Funding
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Abstract
Antihypertensive treatment in diabetes mellitus, especially in diabetics known to have cardiac autonomic neuropathy, may have to consider the status of the autonomic nervous system. In diabetic subjects with cardiac autonomic neuropathy, vagal activity during the night is often reduced. The reduction results in relative or absolute sympathetic activation, which could increase cardiovascular risk. Pathophysiological and clinical data suggests that antihypertensive treatment should reduce rather than induce sympathetic activity in this setting. Beta blocking agents, ACE inhibitors, calcium antagonists of verapamil or diltiazem type and selective imidazoline receptor agonists reduce sympathetic activity and, therefore, may have a beneficial effect in diabetic patients with disturbed sympathovagal balance.
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