Evidence map›Paper›PMID 17591850›Full record

ArticleAntimicrobial agents and chemotherapy2007

Increasing ceftriaxone resistance and multiple alterations of penicillin-binding proteins among penicillin-resistant Streptococcus pneumoniae isolates in Taiwan.

Cheng-Hsun Chiu, Lin-Hui Su, Yhu-Chering Huang, Jui-Chia Lai, Hsiu-Ling Chen, Tsu-Lan Wu, Tzou-Yien Lin

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cheng-Hsun ChiuDepartment of Pediatrics, Chang Gung Children's Hospital, 5 Fu-Hsin Street, Kweishan 333, Taoyuan, Taiwan. chchiu@adm.cgmh.org.tw
Lin-Hui Su
Yhu-Chering Huang
Jui-Chia Lai
Hsiu-Ling Chen
Tsu-Lan Wu
Tzou-Yien Lin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rate of nonsusceptibility of penicillin-resistant Streptococcus pneumoniae strains to ceftriaxone increased significantly in Taiwan in 2005. Approximately 90% of the ceftriaxone-nonsusceptible isolates were found to be of four major serotypes (serotypes 6B, 14, 19F, and 23F). Seven amino acid alterations in the penicillin-binding protein 2B transpeptidase-encoding region specifically contributed to the resistance.

Indexed as

Amino Acid SubstitutionAminoacyltransferasesAnti-Bacterial AgentsCeftriaxoneDNA PrimersDrug Resistance, BacterialElectrophoresis, Gel, Pulsed-FieldHumansPenicillin-Binding ProteinsPenicillin ResistancePneumococcal InfectionsReverse Transcriptase Polymerase Chain ReactionStreptococcus pneumoniaeTaiwanAminoacyltransferasesAnti-Bacterial AgentsCeftriaxoneDNA Primerspenicillin-binding protein 2b, StreptococcusPenicillin-Binding Proteins

Identifiers

PMID17591850
PMCPMC2043203

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.