Evidence map›Paper›PMID 17591615›Full record

ArticleNucleic acids research2007

iGentifier: indexing and large-scale profiling of unknown transcriptomes.

Achim Fischer, Alistair Lenhard, Heike Tronecker, Yvonne Lorat, Marcel Kraenzle, Oliver Sorgenfrei, Tim Zeppenfeld, Michael Haushalter, Gerhard Vogt, Ulrich Gruene and 4 more

Abstract readEvaluation Study
In one paragraph

Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Barley genomics: An overview.International journal of plant genomics · 2008
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Achim FischerGentana GmbH, Axaron Bioscience AG, Im Neuenheimer Feld 515, D-69120 Heidelberg/FRG. achim.fischer@altanapharma.com
Alistair Lenhard
Heike Tronecker
Yvonne Lorat
Marcel Kraenzle
Oliver Sorgenfrei
Tim Zeppenfeld
Michael Haushalter
Gerhard Vogt
Ulrich Gruene
Annette Meyer
Ulrich Handlbichler
Patrick Schweizer
Leo Gaelweiler

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Development and refinement of methods to analyse differential gene expression has been essential in the progress of molecular biology. A novel approach called iGentifier is presented for profiling known and unknown transcriptomes, thus bypassing a major limitation in microarray analysis. The iGentifier technology combines elements of fragment display (e.g. Differential Display or RMDD) and tag sequencing (e.g. SAGE, MPSS) and allows for analysis of samples in high throughput using current capillary electrophoresis equipment. Application to epidermal tissue of wild-type and mlo5 barley (Hordeum vulgare) plants, infected with powdery mildew [Blumeria graminis (DC.) E.O. Speer f.sp.hordei], led to the identification of several 100 genes induced or repressed upon infection with many well known for their response to fungal pathogens or other stressors. Ten of these genes are suggested to be classified as marker genes for durable resistance mediated by the mlo5 resistance gene.

Indexed as

Gene Expression Regulation, PlantGene Expression ProfilingHordeumReproducibility of ResultsRNA, PlantSequence Tagged SitesRNA, Plant

Identifiers

PMID17591615
PMCPMC1950539

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.