ArticleEnvironmental health perspectives2007
Childhood leukemia in the vicinity of the Geesthacht nuclear establishments near Hamburg, Germany.
Article in Environmental health perspectives, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Geographical variation in dementia: systematic review with meta-analysis.International journal of epidemiology · 2012Pooled it
- A municipality-specific analysis to investigate persistent increased incidence rates of childhood leukaemia near the nuclear power plant of Krümmel in Germany.European journal of epidemiology · 2024Article
- Study Protocol for Radiation Exposure and Cancer Risk Assessment: The Taiwan Nuclear Power Plants and Epidemiology Cohort Study (TNPECS).Journal of epidemiology · 2023Article
- Disproportionate Impacts of Radiation Exposure on Women, Children, and Pregnancy: Taking Back our Narrative.Journal of the history of biology · 2021Article
- Risk Communication Strategies: Lessons Learned from Previous Disasters with a Focus on the Fukushima Radiation Accident.Current environmental health reports · 2016Review
- Emerging Environmental Justice Issues in Nuclear Power and Radioactive Contamination.International journal of environmental research and public health · 2016Article
- Childhood leukaemia and nuclear installations: the long and winding road.British journal of cancer · 2014Article
- Epidemiological evidence of childhood leukaemia around nuclear power plants.Dose-response : a publication of International Hormesis Society · 2014Article
- The risk of leukaemia in young children from exposure to tritium and carbon-14 in the discharges of German nuclear power stations and in the fallout from atmospheric nuclear weapons testing.Radiation and environmental biophysics · 2014Article
- Leukaemia in young children in the vicinity of British nuclear power plants: a case-control study.British journal of cancer · 2013Article
- Cancer risks near nuclear facilities: the importance of research design and explicit study hypotheses.Environmental health perspectives · 2011Article
- Childhood leukaemia, nuclear sites, and population mixing.British journal of cancer · 2011Review
- Cancer in children residing near nuclear power plants: an open question.Italian journal of pediatrics · 2010Review
- Temporal trends in childhood leukaemia incidence following exposure to radioactive fallout from atmospheric nuclear weapons testing.Radiation and environmental biophysics · 2010Article
- Commentary: childhood cancer near nuclear power stations.Environmental health : a global access science source · 2009Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDuring 1990-1991 a childhood leukemia cluster was observed in the sparsely populated region surrounding two nuclear establishments southeast of Hamburg, Germany. Since then, several new cases have been reported. Recently a possible accidental release of radionuclides in 1986 was hypothesized.
objectiveThe objective of this study was to analyze the childhood leukemia incidence in this area since 1990.
methodsAll incident cases (< 15 years of age) were ascertained during 1990-2005 within a 5-km radius of the Krümmel nuclear power plant. We derived standardized incidence ratios (SIRs) using county and national leukemia incidence rates as referents. We stratified analyses by calendar period and attained age, and by subdividing the study region into areas north versus south of the Elbe river.
resultsFourteen cases were ascertained in the study area, whereas 4.0 were expected based on national referent rates [1990-2005: SIR = 3.5; 95% confidence interval (CI), 1.9-5.9]. The excess was not confined to the early 1990s; for the more recent time period 1999-2005, the SIR is still elevated (SIR = 2.7; 95% CI, 0.9-6.2). SIRs of greatest magnitude were observed for children 0-4 years of age (SIR = 4.9; 95% CI, 2.4-9.0) and for residents south of the Elbe (SIR = 7.5; 95% CI, 2.8-16.4).
conclusionsThe incidence in this region is significantly higher than the childhood leukemia incidence for Germany as a whole. To date, no unique hazards have been identified in this population. The fact that the elevated rates have persisted in this community for > 15 years warrants further investigation.
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