ArticleEnvironmental health perspectives2007
Declines in sex ratio at birth and fetal deaths in Japan, and in U.S. whites but not African Americans.
Article in Environmental health perspectives, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 81 citations in OpenAlex.
- The Role of Maternal Preconception Adiposity in Human Offspring Sex and Sex Ratio.American journal of epidemiology · 2023Trial
- Cohort profile: The Japan Environment and Children's Study.International journal of epidemiology · 2026Article
- Article
- Extended exposure to tetrabromobisphenol A-bis(2,3-dibromopropyl ether) leads to subfertility in male mice at the late reproductive age.Archives of toxicology · 2023Article
- Changes in the live birth profile in Henan, China: A hospital registry-based study.Birth (Berkeley, Calif.) · 2022Article
- A preliminary analysis of the secondary sex ratio decline after the COVID-19 pandemic in Japan.American journal of human biology : the official journal of the Human Biology Council · 2022Article
- Effects of Socio-demographic Factors on the Decreasing Trend in the Sex Ratio at Birth in Korea, 1997-2017.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2020Article
- The aryl hydrocarbon receptor mediates sex ratio distortion in the embryos sired by TCDD-exposed male mice.Reproductive toxicology (Elmsford, N.Y.) · 2020Article
- Endocrine disrupting chemicals: Impact on human health, wildlife and the environment.Science progress · 2019Review
- Kuopio birth cohort - design of a Finnish joint research effort for identification of environmental and lifestyle risk factors for the wellbeing of the mother and the newborn child.BMC pregnancy and childbirth · 2018Article
- Maternal and paternal serum concentrations of persistent organic pollutants and the secondary sex ratio: A population-based preconception cohort study.Environmental research · 2018Article
- Live birth sex ratios and father's geographic origins in Jerusalem, 1964-1976.American journal of human biology : the official journal of the Human Biology Council · 2017Article
- Preconception stress and the secondary sex ratio in a population-based preconception cohort.Fertility and sterility · 2017Article
- Effects of Fetal Exposure to Asian Sand Dust on Development and Reproduction in Male Offspring.International journal of environmental research and public health · 2016Article
- Secondary sex ratio in regions severely exposed to methylmercury "Minamata disease".International archives of occupational and environmental health · 2016Article
- Couples' urinary concentrations of benzophenone-type ultraviolet filters and the secondary sex ratio.The Science of the total environment · 2016Article
- Endocrine actions of pesticides measured in the Flemish environment and health studies (FLEHS I and II).Environmental science and pollution research international · 2015Article
- Maternal and paternal serum concentrations of perfluoroalkyl and polyfluoroalkyl substances and the secondary sex ratio.Chemosphere · 2015Article
- Couples' urinary bisphenol A and phthalate metabolite concentrations and the secondary sex ratio.Environmental research · 2015Article
- Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe expected ratio of male to female births is generally believed to be 1.05, also described as the male proportion of 0.515.
objectivesWe describe trends in sex ratio at birth and in fetal deaths in the United States, in African Americans and in whites, and in Japan, two industrial countries with well-characterized health data infrastructures, and we speculate about possible explanations.
methodsPublic health records from national statistical agencies were assembled to create information on sex ratio at birth and in fetal deaths in the United States (1970-2002) and Japan (1970-1999), using SPSS.
resultsSex ratio at birth has declined significantly in Japan and in U.S. whites, but not for African Americans, for whom sex ratio remains significantly lower than that of whites. The male proportion of fetal death has increased overall in Japan and in the United States.
conclusionsSex ratio declines are equivalent to a shift from male to female births of 135,000 white males in the United States and 127,000 males in Japan. Known and hypothesized risk factors for reduced sex ratio at birth and in fetal deaths cannot account fully for recent trends or racial or national differences. Whether avoidable environmental or other factors--such as widespread exposure to metalloestrogens or other known or suspected endocrine-disrupting materials, changes in parental age, obesity, assisted reproduction, or nutrition--may account for some of these patterns is a matter that merits serious concern.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.