ReviewJournal of mammary gland biology and neoplasia2007
Modeling metastatic breast cancer in mice.
Review in Journal of mammary gland biology and neoplasia, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 62 citations in OpenAlex.
- Isoliquiritigenin: A natural compound with a promising role in inhibiting breast cancer lung metastasis.Journal of traditional and complementary medicine · 2025Article
- Breast cancer preclinical models: a vital resource for comprehending disease mechanisms and therapeutic development.EXCLI journal · 2025Review
- Experimental Induction of Mammary Carcinogenesis Using 7,12-Dimethylbenz(a)anthracene and Xenograft in Rats.Cureus · 2025Article
- Review
- Karyotype Aberrations in Action: The Evolution of Cancer Genomes and the Tumor Microenvironment.Genes · 2021Review
- Simultaneously targeting cancer-associated fibroblasts and angiogenic vessel as a treatment for TNBC.The Journal of experimental medicine · 2021Article
- Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis.Scientific reports · 2020Article
- Breast cancer animal models and applications.Zoological research · 2020Review
- Expression of Diverse Angiogenesis Factor in Different Stages of the 4T1 Tumor as a Mouse Model of Triple-Negative Breast Cancer.Advanced pharmaceutical bulletin · 2020Article
- Actein Inhibits Tumor Growth and Metastasis in HER2-Positive Breast Tumor Bearing Mice via Suppressing AKT/mTOR and Ras/Raf/MAPK Signaling Pathways.Frontiers in oncology · 2020Article
- Dual complementary liposomes inhibit triple-negative breast tumor progression and metastasis.Science advances · 2019Article
- Degradation of tumour stromal hyaluronan by small extracellular vesicle-PH20 stimulates CD103Journal of extracellular vesicles · 2019Article
- Transparent reporting of experimental parameters in assays measuring phenotypic steps in metastasis.Clinical & experimental metastasis · 2018Article
- Anti-inflammatory signaling by mammary tumor cells mediates prometastatic macrophage polarization in an innovative intraductal mouse model for triple-negative breast cancer.Journal of experimental & clinical cancer research : CR · 2018Article
- A Fibroblast Growth Factor Antagonist Peptide Inhibits Breast Cancer in BALB/c Mice.Open life sciences · 2018Article
- MIND model for triple-negative breast cancer in syngeneic mice for quick and sequential progression analysis of lung metastasis.PloS one · 2018Article
- TGFβ modulates inflammatory cytokines and growth factors to create premetastatic microenvironment and stimulate lung metastasis.Journal of molecular histology · 2015Article
- Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase.The Journal of pathology · 2015Article
- Lobular breast cancer: molecular basis, mouse and cellular models.Breast cancer research : BCR · 2015Article
- Animal models for exploring the pharmacokinetics of breast cancer therapies.Expert opinion on drug metabolism & toxicology · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metastatic disease is the major cause of death in breast cancer patients. Patients presenting with metastases cannot be cured, and as a consequence, treatment is palliative and focuses on prolonging survival and maintaining quality of life. Numerous mouse models have been generated in which human breast cancer development and metastasis have been studied, ranging from spontaneous and carcinogen-induced models to transplantation models and genetically engineered mouse models. Here, we summarize past progress and highlight present developments in modeling breast cancer invasion and metastasis in genetically modified mice, and the impact it may have on the development of innovative anticancer therapies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.