Evidence map›Paper›PMID 17586827›Full record

ArticleBioinformatics (Oxford, England)2007

HaploBuild: an algorithm to construct non-contiguous associated haplotypes in family based genetic studies.

Jason M Laramie, Jemma B Wilk, Anita L DeStefano, Richard H Myers

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Superior haplotypes for transforming crop breeding.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
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  13. Systematic haplotype analysis resolves a complex plasma plant sterol locus on the Micronesian Island of Kosrae.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jason M LaramieDepartment of Neurology, Boston University School of Medicine, Boston, MA, USA. laramiej@bu.edu
Jemma B Wilk
Anita L DeStefano
Richard H Myers

Funding

Epidemiological and Genetic Studies of Body Mass IndexR01HL068891 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI MYERS, RICHARD H · 2002 to 2007
$4.0M
NHLBI NIH HHS R01 HL068891NHLBI NIH HHS R0-1 HL68891-05
6 · The paper itself

Abstract

unlabelledWe have created a program that searches densely genotyped regions for associated non-contiguous haplotypes using a standard family based haplotype association test. This program was designed to expand upon the 'sliding window' methodologies commonly used for haplotype construction by allowing the association of subsets of single nucleotide polymorphisms (SNPs) to drive the construction of the haplotype. This strategy permits HaploBuild to construct more biologically relevant haplotypes that are not constrained by arbitrary length and contiguous orientation. AVAILABILITY: http://snp.bumc.bu.edu.

Indexed as

AlgorithmsGenetics, PopulationPedigreeBiological EvolutionContig MappingFamilyGenetic LinkageGenetic VariationHaplotypesSoftware

Identifiers

PMID17586827
PMCPMC2665175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.