Evidence map›Paper›PMID 17586823›Full record

ArticleNucleic acids research2007

ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry.

Leonid Zamdborg, Richard D LeDuc, Kevin J Glowacz, Yong-Bin Kim, Vinayak Viswanathan, Ian T Spaulding, Bryan P Early, Eric J Bluhm, Shannee Babai, Neil L Kelleher

Abstract read
In one paragraph

Article in Nucleic acids research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. ResNeXt-Based Rescoring Model for Proteoform Characterization in Top-Down Mass Spectra.Interdisciplinary sciences, computational life sciences · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Direct Identification of Intact Proteins Using a Low-Resolution Mass Spectrometer with CIDJournal of the American Society for Mass Spectrometry · 2024
    Article
  11. Article
  12. Article
  13. Top-down proteomics.Nature reviews. Methods primers · 2024
    Article
  14. Article
  15. Journal of the American Society for Mass Spectrometry · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. An Improved Top-Down Mass Spectrometry Characterization ofJournal of the American Society for Mass Spectrometry · 2021
    Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Leonid ZamdborgDepartment of Chemistry, University of Illinois, Urbana, IL 61801, USA.
Richard D LeDuc
Kevin J Glowacz
Yong-Bin Kim
Vinayak Viswanathan
Ian T Spaulding
Bryan P Early
Eric J Bluhm
Shannee Babai
Neil L Kelleher

Funding

The UIUC Neuroproteomics Center on Cell-Cell SignalingP30DA018310 · NIDA · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI Elena V Romanova · 2004 to 2026
$24.9M
Eukaryotic Post-Translational ModificationsR01GM067193 · NIGMS · UNIVERSITY OF ILLINOIS URBANA-CHAMPAIGN · PI KELLEHER, NEIL L · 2003 to 2015
$4.0M
NIDA NIH HHS P30 DA018310NIDA NIH HHS P30 DA 018310-039002NIGMS NIH HHS GM 067193NIGMS NIH HHS R01 GM067193
6 · The paper itself

Abstract

ProSight PTM 2.0 (http://prosightptm2.scs.uiuc.edu) is the next generation of the ProSight PTM web-based system for the identification and characterization of proteins using top down tandem mass spectrometry. It introduces an entirely new data-driven interface, integrated Sequence Gazer for protein characterization, support for fixed modifications, terminal modifications and improved support for multiple precursor ions (multiplexing). Furthermore, it supports data import and export for local analysis and collaboration.

Indexed as

SoftwareComputational BiologyDatabases, ProteinElectronic Data ProcessingHumansInternetMass SpectrometryPolymorphism, GeneticProgramming LanguagesProtein Processing, Post-TranslationalProteinsSequence Analysis, ProteinSequence Tagged SitesUser-Computer InterfaceProteins

Identifiers

PMID17586823
PMCPMC1933126

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.