ArticleBiophysical journal2007
Rigidification of neutral lipid bilayers in the presence of salts.
Article in Biophysical journal, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
65 citing papers in PubMed, 221 citations in OpenAlex.
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- Effects of Lipid Headgroups on the Mechanical Properties and In Vitro Cellular Internalization of Liposomes.Langmuir : the ACS journal of surfaces and colloids · 2025Article
- A Coarse-Grained SPICA Makeover for Solvated and Bare Sodium and Chloride Ions.Journal of chemical theory and computation · 2024Article
- Overcoming the Low-Stability Bottleneck in the Clinical Translation of Liposomal Pressurized Metered-Dose Inhalers: A Shell Stabilization Strategy Inspired by Biomineralization.International journal of molecular sciences · 2024Review
- Environmental Stability and Transmissibility of Enveloped Viruses at Varied Animate and Inanimate Interfaces.Environment & health (Washington, D.C.) · 2023Review
- Calcium-induced compaction and clustering of vesicles tracked with molecular resolution.Biophysical journal · 2023Article
- Passive and reversible area regulation of supported lipid bilayers in response to fluid flow.Biophysical journal · 2023Article
- Cooperativity between sodium ions and water molecules facilitates lipid mobility in model cell membranes.Chemical science · 2023Article
- Interactions of Bacterial Quorum Sensing Signals with Model Lipid Membranes: Influence of Membrane Composition on Membrane Remodeling.Langmuir : the ACS journal of surfaces and colloids · 2023Article
- Structure of POPC Lipid Bilayers in OPLS3e Force Field.Journal of chemical information and modeling · 2022Article
- The role of ion-lipid interactions and lipid packing in transient defects caused by phenolic compounds.Biophysical journal · 2022Article
- High-Dimensional Parameter Search Method to Determine Force Field Mixing Terms in Molecular Simulations.Langmuir : the ACS journal of surfaces and colloids · 2022Article
- Cations Do Not Alter the Membrane Structure of POPC-A Lipid With an Intermediate Area.Frontiers in molecular biosciences · 2022Article
- Lipid specificity of the immune effector perforin.Faraday discussions · 2021Article
- Large scale model lipid membrane movement induced by a cation switch.Journal of colloid and interface science · 2021Article
- Charge Effects Provide Ångström-Level Control of Lipid Bilayer Morphology on Titanium Dioxide Surfaces.Langmuir : the ACS journal of surfaces and colloids · 2021Article
- Relative humidity in droplet and airborne transmission of disease.Journal of biological physics · 2021Review
- Fluid dynamics and epidemiology: Seasonality and transmission dynamics.Physics of fluids (Woodbury, N.Y. : 1994) · 2021Article
- Humidity and Deposition Solution Play a Critical Role in Virus Inactivation by Heat Treatment of N95 Respirators.mSphere · 2020Article
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We studied the influence of sodium and calcium chloride on the global and local membrane properties of fluid palmitoyl-oleoyl phosphatidylcholine bilayers, applying synchrotron small-angle x-ray diffraction, spin-labeling electron paramagnetic resonance spectroscopy, and differential scanning calorimetry, as well as simultaneous density and acoustic measurements. The salt concentration was varied over a wide range from 0 to 5 M. We found that NaCl leads to a continuous swelling of the bilayers, whereas the behavior of the bilayer separation dW in the presence of CaCl2 is more complex, showing an initial large dW value, which decreased upon further addition of salt and finally increased again in the high concentration regime. This can be understood by a change of balance between electrostatic and van der Waals interactions. We were further able to show that both salts lead to a significant increase of order within the lipid bilayer, leading to a decrease of bilayer elasticity and shift of main phase transition temperature. This effect is more pronounced for Ca2+, and occurs mainly in the high salt-concentration regime. Thus, we were able to reconcile previous controversies between molecular dynamics simulations and x-ray diffraction experiments regarding the effect of salts on neutral lipid bilayers.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.