ArticleJournal of proteome research2007
Proteomic analysis of pancreatic zymogen granules: identification of new granule proteins.
Article in Journal of proteome research, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- A pan-vertebrate signaling motif controls the molecular function of intracellular AQP12.The Journal of cell biology · 2026Article
- The proteomic landscape of stool-derived extracellular vesicles in patients with pre-cancerous lesions and colorectal cancer.Communications biology · 2025Article
- OCaR1 endows exocytic vesicles with autoregulatory competence by preventing uncontrolled Ca2+ release, exocytosis, and pancreatic tissue damage.The Journal of clinical investigation · 2024Article
- Bioinformatics analysis of structures and ligand-bindings of predicted zymogen granule protein observed on Bali cattle (Journal of advanced veterinary and animal research · 2021Article
- Isolation and Proteomics of the Insulin Secretory Granule.Metabolites · 2021Review
- Role of Sphingolipid Signaling in Glomerular Diseases: Focus on DKD and FSGS.Journal of cellular signaling · 2020Article
- News about non-secretory exocytosis: mechanisms, properties, and functions.Journal of molecular cell biology · 2019Review
- Molecular architecture of mouse and human pancreatic zymogen granules: protein components and their copy numbers.Biophysics reports · 2018Article
- MIST1 and PTF1 Collaborate in Feed-Forward Regulatory Loops That Maintain the Pancreatic Acinar Phenotype in Adult Mice.Molecular and cellular biology · 2016Article
- Crystal Structure of the Acid Sphingomyelinase-like Phosphodiesterase SMPDL3B Provides Insights into Determinants of Substrate Specificity.The Journal of biological chemistry · 2016Article
- Imbalanced Rab3D versus Rab27 increases cathepsin S secretion from lacrimal acini in a mouse model of Sjögren's Syndrome.American journal of physiology. Cell physiology · 2016Article
- Spontaneous Pancreatitis Caused by Tissue-Specific Gene Ablation ofCellular and molecular gastroenterology and hepatology · 2015Article
- Structural basis for multiple sugar recognition of Jacalin-related human ZG16p lectin.The Journal of biological chemistry · 2014Article
- Tumor protein D52 controls trafficking of an apical endolysosomal secretory pathway in pancreatic acinar cells.American journal of physiology. Gastrointestinal and liver physiology · 2013Article
- Proteomics as a systems approach to pancreatitis.Pancreas · 2013Review
- A Rab11a-Rab8a-Myo5B network promotes stretch-regulated exocytosis in bladder umbrella cells.Molecular biology of the cell · 2013Article
- Cellular localization and biochemical analysis of mammalian CDC50A, a glycosylated β-subunit for P4 ATPases.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2012Article
- Real-time measurement of F-actin remodelling during exocytosis using Lifeact-EGFP transgenic animals.PloS one · 2012Article
- Article
- Activation of soluble adenylyl cyclase protects against secretagogue stimulated zymogen activation in rat pancreaic acinar cells.PloS one · 2012Article
Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The composition of zymogen granules from rat pancreas was determined by LC-MS/MS. Enriched intragranular content, peripheral membrane, and integral membrane protein fractions were analyzed after one-dimensional SDS-PAGE and tryptic digestion of gel slices. A total of 371 proteins was identified with high confidence, including 84 previously identified granule proteins. The 287 remaining proteins included 37 GTP-binding proteins and effectors, 8 tetraspan membrane proteins, and 22 channels and transporters. Seven proteins, pantophysin, cyclic nucleotide phosphodiesterase, carboxypeptidase D, ecto-nucleotide phosphodiesterase 3, aminopeptidase N, ral, and the potassium channel TWIK-2, were confirmed by immunofluorescence microscopy or by immunoblotting to be new zymogen granule membrane proteins.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.