Evidence map›Paper›PMID 17570047›Full record

ArticleVirus genes2007

TT virus (TTV) genotyping in blood donors and multiple transfused patients in Brazil.

Maria Fernanda de Castro Amarante, Simone Kashima, Dimas Tadeu Covas

Abstract read
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In one paragraph

Article in Virus genes, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Torque teno virus among dialysis and renal-transplant patients.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2015
    Article
  4. Article
  5. Emerging infectious threats to the blood supply: seroepidemiological studies in iran - a review.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2013
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Maria Fernanda de Castro AmaranteLaboratory of Molecular Biology, Regional Blood Center of Ribeirão Preto, Rua Tenente Catão Roxo, 2501, Ribeirao Preto, Sao Paulo 14051-140, Brazil. mfcastro@hemocentro.fmrp.usp.br
Simone Kashima
Dimas Tadeu Covas
MRC Laboratory of Molecular Biology · GBUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TT virus (TTV) is widely distributed in the general population. The objective of the present study was to investigate the prevalence and distribution of TTV genotypes among blood donor candidates and multiple transfused patients in the Southeast region of the state of São Paulo, Brazil. TTV-DNA detection by amplification of a segment of the ORF-1 region, presented a prevalence of 11.9% in 270 serum samples from blood donors, of 46.2% in 18 samples from patients with coagulopathies, and of 31.8% in 15 samples from patients with hemoglobinopathies. When specific primers for the non-coding (UTR) region of the TTV genome were used the prevalences were 50.5%, 95.0%, and 82.0% for blood donors, patients with coagulopathies and patients with hemoglobinopathies, respectively. Positive samples from 49 individuals were sequenced and partial segments of 230 base pairs referring to the ORF-1 region of the TTV genome were used for the determination of their genotypes with the aid of phylogenetic analysis. The most frequent genotype was 1 (74.0%), followed by genotype 2 (26.0%). These data indicate a high prevalence of this virus in the populations of blood donors and transfused patients, providing further evidence for the role of transfusions as an efficient pathway in the transmission chain.

Indexed as

Blood DonorsTransfusion ReactionAdultBloodBlood Coagulation DisordersBrazilCluster AnalysisDNA, ViralDNA Virus InfectionsFemaleGenotypeHemoglobinopathiesHumansMaleMiddle AgedMolecular Sequence DataDNA, Viral

Identifiers

PMID17570047
OpenAlexW2083776307

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.